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Leoligin-inspired synthetic lignans with selectivity for cell-type and bioactivity relevant for cardiovascular disease
Recently, a natural compound leoligin, a furan-type lignan, was discovered as an interesting hit compound with an anti-inflammatory pharmacological activity profile. We developed a modular and stereoselective approach for the synthesis of the edelweiss-derived lignan leoligin and used the synthetic...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568278/ https://www.ncbi.nlm.nih.gov/pubmed/31293770 http://dx.doi.org/10.1039/c9sc00446g |