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Neonatal Hyperglycemia, which threshold value, diagnostic approach and treatment?: Turkish Neonatal and Pediatric Endocrinology and Diabetes Societies consensus report

Hyperglycemia has become an important risk factor for mortality and morbidity in the neonatal period, especially with increased survival rates of very low birth weight neonates. Hyperglycemia in the neonatal period develops as a result of various mechanisms including iatrogenic causes, inability to...

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Autores principales: Şimşek, Damla Gökşen, Ecevit, Ayşe, Hatipoğlu, Nihal, Çoban, Asuman, Arısoy, Ayşe Engin, Baş, Firdevs, Mutlu, Gül Yeşiltepe, Bideci, Aysun, Özek, Eren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kare Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568286/
https://www.ncbi.nlm.nih.gov/pubmed/31236036
http://dx.doi.org/10.5152/TurkPediatriArs.2018.01821
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author Şimşek, Damla Gökşen
Ecevit, Ayşe
Hatipoğlu, Nihal
Çoban, Asuman
Arısoy, Ayşe Engin
Baş, Firdevs
Mutlu, Gül Yeşiltepe
Bideci, Aysun
Özek, Eren
author_facet Şimşek, Damla Gökşen
Ecevit, Ayşe
Hatipoğlu, Nihal
Çoban, Asuman
Arısoy, Ayşe Engin
Baş, Firdevs
Mutlu, Gül Yeşiltepe
Bideci, Aysun
Özek, Eren
author_sort Şimşek, Damla Gökşen
collection PubMed
description Hyperglycemia has become an important risk factor for mortality and morbidity in the neonatal period, especially with increased survival rates of very low birth weight neonates. Hyperglycemia in the neonatal period develops as a result of various mechanisms including iatrogenic causes, inability to supress hepatic glucose production, insulin resistance or glucose intolerance, specifically in preterm neonates. Initiation of parenteral or enteral feeding in the early period in preterm babies increases insulin production and sensitivity. The plasma glucose is targeted to be kept between 70 and 150 mg/dL in the newborn baby. While a blood glucose value above 150 mg/dL is defined as hyperglycemia, blood glucose values measured with an interval of 4 hours of >180-200 mg/dL and +2 glucosuria require treatment. Although glucose infusion rate is reduced in treatment, use of insulin is recommended, if two blood glucose values measured with an interval of 4 hours are >250 mg/dL and glucosuria is present in two separate urine samples.
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spelling pubmed-65682862019-06-24 Neonatal Hyperglycemia, which threshold value, diagnostic approach and treatment?: Turkish Neonatal and Pediatric Endocrinology and Diabetes Societies consensus report Şimşek, Damla Gökşen Ecevit, Ayşe Hatipoğlu, Nihal Çoban, Asuman Arısoy, Ayşe Engin Baş, Firdevs Mutlu, Gül Yeşiltepe Bideci, Aysun Özek, Eren Turk Pediatri Ars Article Hyperglycemia has become an important risk factor for mortality and morbidity in the neonatal period, especially with increased survival rates of very low birth weight neonates. Hyperglycemia in the neonatal period develops as a result of various mechanisms including iatrogenic causes, inability to supress hepatic glucose production, insulin resistance or glucose intolerance, specifically in preterm neonates. Initiation of parenteral or enteral feeding in the early period in preterm babies increases insulin production and sensitivity. The plasma glucose is targeted to be kept between 70 and 150 mg/dL in the newborn baby. While a blood glucose value above 150 mg/dL is defined as hyperglycemia, blood glucose values measured with an interval of 4 hours of >180-200 mg/dL and +2 glucosuria require treatment. Although glucose infusion rate is reduced in treatment, use of insulin is recommended, if two blood glucose values measured with an interval of 4 hours are >250 mg/dL and glucosuria is present in two separate urine samples. Kare Publishing 2018-12-25 /pmc/articles/PMC6568286/ /pubmed/31236036 http://dx.doi.org/10.5152/TurkPediatriArs.2018.01821 Text en Copyright: © 2018 Turkish Pediatric Association http://creativecommons.org/licenses/by-nc-sa/4.0 This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
spellingShingle Article
Şimşek, Damla Gökşen
Ecevit, Ayşe
Hatipoğlu, Nihal
Çoban, Asuman
Arısoy, Ayşe Engin
Baş, Firdevs
Mutlu, Gül Yeşiltepe
Bideci, Aysun
Özek, Eren
Neonatal Hyperglycemia, which threshold value, diagnostic approach and treatment?: Turkish Neonatal and Pediatric Endocrinology and Diabetes Societies consensus report
title Neonatal Hyperglycemia, which threshold value, diagnostic approach and treatment?: Turkish Neonatal and Pediatric Endocrinology and Diabetes Societies consensus report
title_full Neonatal Hyperglycemia, which threshold value, diagnostic approach and treatment?: Turkish Neonatal and Pediatric Endocrinology and Diabetes Societies consensus report
title_fullStr Neonatal Hyperglycemia, which threshold value, diagnostic approach and treatment?: Turkish Neonatal and Pediatric Endocrinology and Diabetes Societies consensus report
title_full_unstemmed Neonatal Hyperglycemia, which threshold value, diagnostic approach and treatment?: Turkish Neonatal and Pediatric Endocrinology and Diabetes Societies consensus report
title_short Neonatal Hyperglycemia, which threshold value, diagnostic approach and treatment?: Turkish Neonatal and Pediatric Endocrinology and Diabetes Societies consensus report
title_sort neonatal hyperglycemia, which threshold value, diagnostic approach and treatment?: turkish neonatal and pediatric endocrinology and diabetes societies consensus report
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568286/
https://www.ncbi.nlm.nih.gov/pubmed/31236036
http://dx.doi.org/10.5152/TurkPediatriArs.2018.01821
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