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Hydroxyurea-Induced miRNA Expression in Sickle Cell Disease Patients in Africa

Hydroxyurea (HU) is clinically beneficial in sickle cell disease (SCD) through fetal hemoglobin (HbF) induction; however, the mechanism of HU is not yet fully elucidated. Selected miRNAs have been associated with HU-induced HbF production. We have investigated differential HU-induced global miRNA ex...

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Detalles Bibliográficos
Autores principales:	Mnika, Khuthala, Mazandu, Gaston K., Jonas, Mario, Pule, Gift D., Chimusa, Emile R., Hanchard, Neil A., Wonkam, Ambroise
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568309/ https://www.ncbi.nlm.nih.gov/pubmed/31231425 http://dx.doi.org/10.3389/fgene.2019.00509

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