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microRNA-200c regulates KLOTHO expression in human kidney cells under oxidative stress
KLOTHO deficiency is associated with the progression of kidney dysfunction, whereas its overexpression exerts renoprotective effects. Oxidative stress suppresses KLOTHO expression in renal epithelial cells but upregulates microRNA-200c (miR-200c) in human umbilical vein endothelial cells. In this st...
Autores principales: | Morii, Kenichi, Yamasaki, Satoshi, Doi, Shigehiro, Irifuku, Taisuke, Sasaki, Kensuke, Doi, Toshiki, Nakashima, Ayumu, Arihiro, Koji, Masaki, Takao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568409/ https://www.ncbi.nlm.nih.gov/pubmed/31199854 http://dx.doi.org/10.1371/journal.pone.0218468 |
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