4-(N,N-dipropylamino)benzaldehyde inhibits the oxidation of all-trans retinal to all-trans retinoic acid by ALDH1A1, but not the differentiation of HL-60 promyelocytic leukemia cells exposed to all-trans retinal

BACKGROUND: The signal transduction pathways mediated by retinoic acid play a critical role in the regulation of cell growth and differentiation during embryogenesis and hematopoiesis as well as in a variety of tumor cell lines in culture. Following the reports that two members of the superfamily of...

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Detalles Bibliográficos
Autores principales: Russo, James, Barnes, Annette, Berger, Katie, Desgrosellier, Jay, Henderson, Jennifer, Kanters, Ana, Merkov, Lubo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC65698/
https://www.ncbi.nlm.nih.gov/pubmed/11872149
http://dx.doi.org/10.1186/1471-2210-2-4

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