Regulation of GLI1 by cis DNA elements and epigenetic marks

GLI1 is one of three transcription factors (GLI1, GLI2 and GLI3) that mediate the Hedgehog signal transduction pathway and play important roles in normal development. GLI1 and GLI2 form a positive-feedback loop and function as human oncogenes. The mouse and human GLI1 genes have untranslated 5′ exon...

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Detalles Bibliográficos
Autores principales: Taylor, Robert, Long, Jun, Yoon, Joon Won, Childs, Ronnie, Sylvestersen, Kathrine B., Nielsen, Michael L., Leong, King-Fu, Iannaccone, Stephen, Walterhouse, David O., Robbins, David J., Iannaccone, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570425/
https://www.ncbi.nlm.nih.gov/pubmed/31085420
http://dx.doi.org/10.1016/j.dnarep.2019.04.011

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