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Stem cells in human breast milk

Recent studies have demonstrated that breast milk contains a population of cells displaying many of the properties typical of stem cells. This review outlines progress made in this newly emerging field of stem cell biology and provides an analysis of the available data on purification, propagation a...

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Autores principales: Ninkina, Natalia, Kukharsky, Michail S., Hewitt, Maria V., Lysikova, Ekaterina A., Skuratovska, Larissa N., Deykin, Alexey V., Buchman, Vladimir L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570695/
https://www.ncbi.nlm.nih.gov/pubmed/30972555
http://dx.doi.org/10.1007/s13577-019-00251-7
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author Ninkina, Natalia
Kukharsky, Michail S.
Hewitt, Maria V.
Lysikova, Ekaterina A.
Skuratovska, Larissa N.
Deykin, Alexey V.
Buchman, Vladimir L.
author_facet Ninkina, Natalia
Kukharsky, Michail S.
Hewitt, Maria V.
Lysikova, Ekaterina A.
Skuratovska, Larissa N.
Deykin, Alexey V.
Buchman, Vladimir L.
author_sort Ninkina, Natalia
collection PubMed
description Recent studies have demonstrated that breast milk contains a population of cells displaying many of the properties typical of stem cells. This review outlines progress made in this newly emerging field of stem cell biology and provides an analysis of the available data on purification, propagation and differentiation of certain types of progenitor cells from breast milk. The possible fates of breast milk cells, including microchimerism caused by their transmission to the distant organs of the infant, are also discussed. Unique properties of breast milk-derived stem cells, such as their unusually low tumorigenic potential and their negligible ability to form teratomas, are highlighted as obvious advantages for using these cells in regenerative therapy.
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spelling pubmed-65706952019-07-01 Stem cells in human breast milk Ninkina, Natalia Kukharsky, Michail S. Hewitt, Maria V. Lysikova, Ekaterina A. Skuratovska, Larissa N. Deykin, Alexey V. Buchman, Vladimir L. Hum Cell Review Article Recent studies have demonstrated that breast milk contains a population of cells displaying many of the properties typical of stem cells. This review outlines progress made in this newly emerging field of stem cell biology and provides an analysis of the available data on purification, propagation and differentiation of certain types of progenitor cells from breast milk. The possible fates of breast milk cells, including microchimerism caused by their transmission to the distant organs of the infant, are also discussed. Unique properties of breast milk-derived stem cells, such as their unusually low tumorigenic potential and their negligible ability to form teratomas, are highlighted as obvious advantages for using these cells in regenerative therapy. Springer Japan 2019-04-10 2019 /pmc/articles/PMC6570695/ /pubmed/30972555 http://dx.doi.org/10.1007/s13577-019-00251-7 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Review Article
Ninkina, Natalia
Kukharsky, Michail S.
Hewitt, Maria V.
Lysikova, Ekaterina A.
Skuratovska, Larissa N.
Deykin, Alexey V.
Buchman, Vladimir L.
Stem cells in human breast milk
title Stem cells in human breast milk
title_full Stem cells in human breast milk
title_fullStr Stem cells in human breast milk
title_full_unstemmed Stem cells in human breast milk
title_short Stem cells in human breast milk
title_sort stem cells in human breast milk
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570695/
https://www.ncbi.nlm.nih.gov/pubmed/30972555
http://dx.doi.org/10.1007/s13577-019-00251-7
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