Cargando…

Signaling pathways involved in chronic myeloid leukemia pathogenesis: The importance of targeting Musashi2-Numb signaling to eradicate leukemia stem cells

OBJECTIVE(S): Chronic myeloid leukemia (CML) is a myeloid clonal proliferation disease defining by the presence of the Philadelphia chromosome that shows the movement of BCR-ABL1. In this study, the critical role of the Musashi2-Numb axis in determining cell fate and relationship of the axis to impo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Moradi, Foruzan, Babashah, Sadegh, Sadeghizadeh, Majid, Jalili, Arsalan, Hajifathali, Abbas, Roshandel, Hajifathali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mashhad University of Medical Sciences 2019
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570743/ https://www.ncbi.nlm.nih.gov/pubmed/31231484 http://dx.doi.org/10.22038/ijbms.2019.31879.7666

Ejemplares similares

Association of Interleukin 10 (IL-10) Gene Polymorphism (819T > C) with Susceptibility to Acute Myeloid Leukemia: A Meta-Analysis
por: Ahadi, Hamid Reza, et al.
Publicado: (2022)

HOTAIR Long Noncoding RNA is not a Biomarker for Acute Myeloid Leukemia (AML) in Iranian Patients
por: Sayad, Arezou, et al.
Publicado: (2017)

The Impact of Different Cell Culture Mediums on CD8+T Cells Expansion: A Bioinformatics Study
por: Jalili, Arsalan, et al.
Publicado: (2022)

Assessment of the Effect of Infliximab on Immunomodulation Properties of Mesenchymal Stem Cells In Vitro
por: Sakha, Yasaman Aliasghari, et al.
Publicado: (2021)

Fas-Antisense Long Noncoding RNA and Acute Myeloid Leukemia: Is There any Relation?
por: Sayad, Arezou, et al.
Publicado: (2018)

Regulation of myeloid leukemia by the cell fate determinant Musashi
por: Ito, Takahiro, et al.
Publicado: (2010)

Virus-Specific T Cells: Promising Adoptive T Cell Therapy Against Infectious Diseases Following Hematopoietic Stem Cell Transplantation
por: Jalili, Arsalan, et al.
Publicado: (2023)

Survival of Patients with Acute Myeloid Leukemia after Allogeneic Stem Cell Transplantation: An Experience in Developing Country
por: Mehdizadeh, Mahshid, et al.
Publicado: (2022)

Impact of Musashi-1 and Musashi-2 Double Knockdown on Notch Signaling and the Pathogenesis of Endometriosis
por: Strauß, Theresa, et al.
Publicado: (2022)

Hsp70, in Combination with IL-15 and PD-1 Blocker, Interferes with The Induction of Cytotoxic NK Cells in Relapsed Acute Myeloid Leukemia Patients
por: Firouzi, Javad, et al.
Publicado: (2023)

Musashi1 expression is negatively correlated with numb expression in brain metastases
por: Dong, Yalan, et al.
Publicado: (2020)

Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia
por: Minuesa, Gerard, et al.
Publicado: (2019)

Plasma exchange followed by convalescent plasma transfusion in COVID-19 patients
por: Roshandel, Elham, et al.
Publicado: (2021)

Monocytes educated by cancer-associated fibroblasts secrete exosomal miR-181a to activate AKT signaling in breast cancer cells
por: Pakravan, Katayoon, et al.
Publicado: (2022)

Oxidative Stress and ROS-Mediated Signaling in Leukemia: Novel Promising Perspectives to Eradicate Chemoresistant Cells in Myeloid Leukemia
por: Trombetti, Silvia, et al.
Publicado: (2021)

Musashi2 promotes the development and progression of pancreatic cancer by down-regulating Numb protein
por: Sheng, Weiwei, et al.
Publicado: (2016)

The Involvement of Canonical NFκB Pathway in Megakaryocyte Differentiation Induction by Nanocurcumin
por: Mortazavi Farsani, Seyedeh Sahar, et al.
Publicado: (2023)

Correction: Musashi2 promotes the development and progression of pancreatic cancer by down-regulating Numb protein
por: Sheng, Weiwei, et al.
Publicado: (2022)

Acute Myeloid Leukemia Presenting with Numb Chin Syndrome: A Case Report and Review of Literature
por: Babikir, Mona M., et al.
Publicado: (2020)

Musashi-2 Silencing Exerts Potent Activity against Acute Myeloid Leukemia and Enhances Chemosensitivity to Daunorubicin
por: Han, Yixiang, et al.
Publicado: (2015)

Harnessing the Metabolic Vulnerabilities of Leukemia Stem Cells to Eradicate Acute Myeloid Leukemia
por: Kumar, Bijender
Publicado: (2021)

Dendrosomal nanocurcumin and p53 overexpression synergistically trigger apoptosis in glioblastoma cells
por: Keshavarz, Reihaneh, et al.
Publicado: (2016)

Protective Effects of a Nano-Formulation of Curcumin against Cuprizone-Induced Demyelination in the Mouse Corpus Callosum
por: Motavaf, Mahsa, et al.
Publicado: (2020)

The Association of HLA Class 1 and Class 2 Antigens with Multiple Myeloma in Iranian Patients
por: Sayad, Arezou, et al.
Publicado: (2014)

Association of MTHFR C677T and A1298C Polymorphisms with Susceptibility to Chronic Lymphocytic Leukemia: A Systematic Review and Meta-Analysis
por: RAOUFI, Atefeh, et al.
Publicado: (2021)

The Promising Role of Non-Coding RNAs as Biomarkers and Therapeutic Targets for Leukemia
por: Ghazimoradi, Mohammad H., et al.
Publicado: (2023)

The association of disease type, pre-transplant hemoglobin level and platelet count with transfusion requirement after autologous hematopoietic stem cell transplantation
por: Tabasi, Shabnam, et al.
Publicado: (2021)

MicroRNA-143 acts as a tumor suppressor through Musashi-2/DLL1/Notch1 and Musashi-2/Snail1/MMPs axes in acute myeloid leukemia
por: Li, Fanfan, et al.
Publicado: (2023)

Decidual stromal cell therapy for generalized lymphadenopathy as a special clinical manifestation of COVID‐19 infection: A case report
por: Pirsalehi, Ali, et al.
Publicado: (2022)

Cell-Based Therapy Approaches in Treatment of Non-obstructive Azoospermia
por: Roshandel, Elham, et al.
Publicado: (2022)

Milk thistle nano-micelle formulation promotes cell cycle arrest and apoptosis in hepatocellular carcinoma cells through modulating miR-155-3p /SOCS2 /PHLDA1 signaling axis
por: Rahnama, Saghar, et al.
Publicado: (2023)

SMAD4 contributes to chondrocyte and osteocyte development
por: Pakravan, Katayoon, et al.
Publicado: (2021)

Characterization of TRKA signaling in acute myeloid leukemia
por: Herbrich, Shelley M., et al.
Publicado: (2018)

Association of HScore Parameters with Severe COVID-19: A Systematic Review and Meta-Analysis
por: Hossein Kazemi, Mohammad, et al.
Publicado: (2021)

The effect of granulocyte colony‐stimulating factor dose and administration interval after allogeneic hematopoietic cell transplantation on early engraftment of neutrophil and platelet
por: Noorazar, Leila, et al.
Publicado: (2021)

Plasma levels of norepinephrine and expression levels of ß2-adrenergic receptor gene correlate with the incidence of acute graft-versus-host disease
por: Momeni-Varposhti, Zahra, et al.
Publicado: (2020)

Risk Factors of Graft-Versus-Host Disease in the Iranian Allogeneic Hematopoietic Stem Cell Transplantation: A 10-Year Experience
por: Mehdizadeh, Mahshid, et al.
Publicado: (2021)

Musashi-1 Post-Transcriptionally Enhances Phosphotyrosine-Binding Domain-Containing m-Numb Protein Expression in Regenerating Gastric Mucosa
por: Takahashi, Tetsufumi, et al.
Publicado: (2013)

Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia
por: Hu, Cheng-Long, et al.
Publicado: (2022)

Expansion of CD133(+) Umbilical Cord Blood Derived Hematopoietic Stem Cells on a Biocompatible Microwells
por: Soufizomorrod, Mina, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_54g752ss33ihm219q0jrnlf0qk