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Stochastic changes in gene expression promote chaotic dysregulation of homeostasis in clonal breast tumors
Cells within tumors vary in phenotype as a result of changes in gene expression caused by a variety of mechanisms, permitting cancers to evolve under selective pressures from immune and other homeostatic processes. Earlier, we traced apparent losses in heterozygosity (LOH) of spontaneous breast tumo...
Autores principales: | Felts, Sara J., Tang, Xiaojia, Willett, Benjamin, Van Keulen, Virginia P., Hansen, Michael J., Kalari, Krishna R., Pease, Larry R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570763/ https://www.ncbi.nlm.nih.gov/pubmed/31240244 http://dx.doi.org/10.1038/s42003-019-0460-0 |
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