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Stochastic changes in gene expression promote chaotic dysregulation of homeostasis in clonal breast tumors

Cells within tumors vary in phenotype as a result of changes in gene expression caused by a variety of mechanisms, permitting cancers to evolve under selective pressures from immune and other homeostatic processes. Earlier, we traced apparent losses in heterozygosity (LOH) of spontaneous breast tumo...

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Detalles Bibliográficos
Autores principales: Felts, Sara J., Tang, Xiaojia, Willett, Benjamin, Van Keulen, Virginia P., Hansen, Michael J., Kalari, Krishna R., Pease, Larry R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570763/
https://www.ncbi.nlm.nih.gov/pubmed/31240244
http://dx.doi.org/10.1038/s42003-019-0460-0

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