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In situ structure and assembly of the multidrug efflux pump AcrAB-TolC

Multidrug efflux pumps actively expel a wide range of toxic substrates from the cell and play a major role in intrinsic and acquired drug resistance. In Gram-negative bacteria, these pumps form tripartite assemblies that span the cell envelope. However, the in situ structure and assembly mechanism o...

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Detalles Bibliográficos
Autores principales:	Shi, Xiaodong, Chen, Muyuan, Yu, Zhili, Bell, James M., Wang, Hans, Forrester, Isaac, Villarreal, Heather, Jakana, Joanita, Du, Dijun, Luisi, Ben F., Ludtke, Steven J., Wang, Zhao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570770/ https://www.ncbi.nlm.nih.gov/pubmed/31201302 http://dx.doi.org/10.1038/s41467-019-10512-6

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