Cargando…

miR-520d-5p can reduce the mutations in hepatoma cancer cells and iPSCs-derivatives

BACKGROUND: Human microRNAs (miRNAs) have diverse functions in biology, and play a role in nearly every biological process. Here we report that miR-520d-5p (520d-5p) causes undifferentiated cancer cells to adopt benign or normal status in vivo in immunodeficient mice via demethylation and P53 upregu...

Descripción completa

Detalles Bibliográficos
Autores principales: Miura, Norimasa, Ishihara, Yoshitaka, Miura, Yugo, Kimoto, Mai, Miura, Keigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570841/
https://www.ncbi.nlm.nih.gov/pubmed/31202279
http://dx.doi.org/10.1186/s12885-019-5786-y