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Label-free quantitative proteomics identifies transforming growth factor β1 (TGF-β1) as an inhibitor of adipogenic transformation in OP9-DL1 cells and primary thymic stromal cells
BACKGROUND: Adipocyte accumulation is a predominant feature of age-related thymic involution, but the mechanisms responsible for thymic adipogenesis remain to be elucidated. The aim of this study was to identify key regulators in thymic adipogenesis. We used rosiglitazone, a potent peroxisome prolif...
Autores principales: | Tan, Jianxin, Wang, Yajun, Wang, Siliang, Wu, Simeng, Yuan, Zhe, Zhu, Xike |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570845/ https://www.ncbi.nlm.nih.gov/pubmed/31249661 http://dx.doi.org/10.1186/s13578-019-0311-1 |
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