ERK1/2 communicates GPCR and EGFR signaling pathways to promote CTGF-mediated hypertrophic cardiomyopathy upon Ang-II stimulation

BACKGROUND: Hypertrophic cardiomyopathy occurs along with pathological phenomena such as cardiac hypertrophy, myocardial fibrosis and cardiomyocyte activity. However, few of the specific molecular mechanisms underlying this pathological condition have been mentioned. METHODS: All target proteins and...

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Detalles Bibliográficos
Autores principales: Liu, Xin, Lin, Lin, Li, Qing, Ni, Yajuan, Zhang, Chaoying, Qin, Shuguang, Wei, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570861/
https://www.ncbi.nlm.nih.gov/pubmed/31200637
http://dx.doi.org/10.1186/s12860-019-0202-7

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