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Viral integration drives multifocal HCC during the occult HBV infection

BACKGROUND & AIMS: Although the prognosis of patients with occult hepatitis B virus (HBV) infection (OBI) is usually benign, a small portion may undergo cirrhosis and subsequently hepatocellular carcinoma (HCC). We studied the mechanism of life-long Integration of virus DNA into OBI host’s genom...

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Detalles Bibliográficos
Autores principales:	Chen, Xiao-Ping, Long, Xin, Jia, Wen-long, Wu, Han-Jie, Zhao, Jing, Liang, Hui-Fang, Laurence, Arian, Zhu, Jun, Dong, Dong, Chen, Yan, Lin, Long, Xia, Yu-Dong, Li, Wei-Yang, Li, Gui-Bo, Zhao, Zhi-Kun, Wu, Kui, Hou, Yong, Yu, Jing-Jing, Xiao, Wei, Wang, Guo-Ping, Zhu, Peng-Cheng, Chen, Wei, Bai, Ming-Zhou, Jian, Yi-Xing, Kristiansen, Karsten, Chen, Qian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570863/ https://www.ncbi.nlm.nih.gov/pubmed/31200735 http://dx.doi.org/10.1186/s13046-019-1273-1

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