Contribution of tissue transglutaminase to the severity of hepatic fibrosis resulting from Schistosoma japonicum infection through the regulation of IL-33/ST2 expression

BACKGROUND: Tissue transglutaminase (tTG)-regulating IL-13 plays an important role in the pathogenesis of liver fibrosis resulting from Schistosoma japonicum (Sj) infection. IL-33 and its receptor ST2 are involved in Th2-biased immune responses through the release of IL-5 and IL-13 and subsequent he...

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Detalles Bibliográficos
Autores principales: Li, Zhi-Yong, Xiao, LinZhuo, Lin, GuiYing, Tang, JuanJuan, Chen, YuQiang, Chen, Lan, Li, BaoQi, Wu, MeiLing, Liu, ShuYan, Huang, ChuQin, Ferrandon, Dominique, Li, Zi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570881/
https://www.ncbi.nlm.nih.gov/pubmed/31200771
http://dx.doi.org/10.1186/s13071-019-3542-4

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