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Impact of patients´ age on short and long-term outcome after carotid endarterectomy and simultaneous coronary artery bypass grafting

BACKGROUND: The purpose of this study was to investigate whether age has an effect on short and long-term outcome in patients who undergo simultaneous coronary artery bypass grafting (CABG) and carotid endarterectomy. METHODS: From 2005 to 2017, 186 consecutive elective patients underwent CABG and s...

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Autores principales: Salehi Ravesh, Mona, Rusch, Rene, Friedrich, Christine, Teickner, Christoph, Berndt, Rouven, Haneya, Assad, Cremer, Jochen, Pühler, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570883/
https://www.ncbi.nlm.nih.gov/pubmed/31202278
http://dx.doi.org/10.1186/s13019-019-0928-5
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author Salehi Ravesh, Mona
Rusch, Rene
Friedrich, Christine
Teickner, Christoph
Berndt, Rouven
Haneya, Assad
Cremer, Jochen
Pühler, Thomas
author_facet Salehi Ravesh, Mona
Rusch, Rene
Friedrich, Christine
Teickner, Christoph
Berndt, Rouven
Haneya, Assad
Cremer, Jochen
Pühler, Thomas
author_sort Salehi Ravesh, Mona
collection PubMed
description BACKGROUND: The purpose of this study was to investigate whether age has an effect on short and long-term outcome in patients who undergo simultaneous coronary artery bypass grafting (CABG) and carotid endarterectomy. METHODS: From 2005 to 2017, 186 consecutive elective patients underwent CABG and synchronous endarterectomy at our institution. Patients were retrospectively classified according to age into 2 groups: patients above 70 years (elderly group: n = 97, 76.1 ± 3.9 years) and patients below 70 years (younger group: n = 89, 63.2 ± 4.8 years). RESULTS: The European System for Cardiac Operative Risk Evaluation (EuroSCORE) II, 4.4% vs. 2.5%; p < 0.001) and Society of Thoracic Surgeons (STS) score (0.7% vs. 1.6%; p < 0.001) were significantly higher in the elderly group. Otherwise, there was no difference between the two groups concerning important preoperative risk factors or the intraoperative data. Postoperatively, the incidence of temporary dialysis was significantly higher in the elderly group (14.4% vs. 3.4%; p = 0.009). The rate of tracheotomy (16.5% vs. 2.2%; p = 0.001), of re-intubation (7.9% vs. 18.6%; p = 0.033) and drainage loss (600 ml vs. 800 ml; p = 0.035) was significantly higher in this elderly group. Neurological complications and 30-day mortality were comparable. Long-term survival was satisfactory for both groups. Nevertheless, 5-year survival rates (63% vs. 85%) were significantly lower in the elderly group (p = 0.003). Logistic regression analysis identified chronic obstructive pulmonary disease (COPD) and arrhythmia as significant risk factors for 30-day-mortality, but not age. CONCLUSIONS: CABG in combination with synchronous endarterectomy can also be performed with satisfactory results in elderly patients. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13019-019-0928-5) contains supplementary material, which is available to authorized users.
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spelling pubmed-65708832019-06-27 Impact of patients´ age on short and long-term outcome after carotid endarterectomy and simultaneous coronary artery bypass grafting Salehi Ravesh, Mona Rusch, Rene Friedrich, Christine Teickner, Christoph Berndt, Rouven Haneya, Assad Cremer, Jochen Pühler, Thomas J Cardiothorac Surg Research Article BACKGROUND: The purpose of this study was to investigate whether age has an effect on short and long-term outcome in patients who undergo simultaneous coronary artery bypass grafting (CABG) and carotid endarterectomy. METHODS: From 2005 to 2017, 186 consecutive elective patients underwent CABG and synchronous endarterectomy at our institution. Patients were retrospectively classified according to age into 2 groups: patients above 70 years (elderly group: n = 97, 76.1 ± 3.9 years) and patients below 70 years (younger group: n = 89, 63.2 ± 4.8 years). RESULTS: The European System for Cardiac Operative Risk Evaluation (EuroSCORE) II, 4.4% vs. 2.5%; p < 0.001) and Society of Thoracic Surgeons (STS) score (0.7% vs. 1.6%; p < 0.001) were significantly higher in the elderly group. Otherwise, there was no difference between the two groups concerning important preoperative risk factors or the intraoperative data. Postoperatively, the incidence of temporary dialysis was significantly higher in the elderly group (14.4% vs. 3.4%; p = 0.009). The rate of tracheotomy (16.5% vs. 2.2%; p = 0.001), of re-intubation (7.9% vs. 18.6%; p = 0.033) and drainage loss (600 ml vs. 800 ml; p = 0.035) was significantly higher in this elderly group. Neurological complications and 30-day mortality were comparable. Long-term survival was satisfactory for both groups. Nevertheless, 5-year survival rates (63% vs. 85%) were significantly lower in the elderly group (p = 0.003). Logistic regression analysis identified chronic obstructive pulmonary disease (COPD) and arrhythmia as significant risk factors for 30-day-mortality, but not age. CONCLUSIONS: CABG in combination with synchronous endarterectomy can also be performed with satisfactory results in elderly patients. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13019-019-0928-5) contains supplementary material, which is available to authorized users. BioMed Central 2019-06-15 /pmc/articles/PMC6570883/ /pubmed/31202278 http://dx.doi.org/10.1186/s13019-019-0928-5 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Salehi Ravesh, Mona
Rusch, Rene
Friedrich, Christine
Teickner, Christoph
Berndt, Rouven
Haneya, Assad
Cremer, Jochen
Pühler, Thomas
Impact of patients´ age on short and long-term outcome after carotid endarterectomy and simultaneous coronary artery bypass grafting
title Impact of patients´ age on short and long-term outcome after carotid endarterectomy and simultaneous coronary artery bypass grafting
title_full Impact of patients´ age on short and long-term outcome after carotid endarterectomy and simultaneous coronary artery bypass grafting
title_fullStr Impact of patients´ age on short and long-term outcome after carotid endarterectomy and simultaneous coronary artery bypass grafting
title_full_unstemmed Impact of patients´ age on short and long-term outcome after carotid endarterectomy and simultaneous coronary artery bypass grafting
title_short Impact of patients´ age on short and long-term outcome after carotid endarterectomy and simultaneous coronary artery bypass grafting
title_sort impact of patients´ age on short and long-term outcome after carotid endarterectomy and simultaneous coronary artery bypass grafting
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570883/
https://www.ncbi.nlm.nih.gov/pubmed/31202278
http://dx.doi.org/10.1186/s13019-019-0928-5
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