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Hippocampal stem cells promotes synaptic resistance to the dysfunctional impact of amyloid beta oligomers via secreted exosomes

BACKGROUND: Adult hippocampal neurogenesis plays an important role in synaptic plasticity and cogntive function. We reported that higher numbers of neural stem cells (NSC) in the hippocampus of cognitively-intact individuals with high Alzheimer’s disease (AD) pathology (plaques and tangles) is assoc...

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Detalles Bibliográficos
Autores principales:	Micci, Maria-Adelaide, Krishnan, Balaji, Bishop, Elizabeth, Zhang, Wen-Ru, Guptarak, Jutatip, Grant, Auston, Zolochevska, Olga, Tumurbaatar, Batbayar, Franklin, Whitney, Marino, Claudia, Widen, Steven G., Luthra, Arjun, Kernie, Steven G., Taglialatela, Giulio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570890/ https://www.ncbi.nlm.nih.gov/pubmed/31200742 http://dx.doi.org/10.1186/s13024-019-0322-8

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