Cargando…

Selective inhibition of histone deacetylase 8 improves vascular hypertrophy, relaxation, and inflammation in angiotensin II hypertensive mice

BACKGROUND: The dysregulation of histone deacetylase (HDAC) protein expression or its enzyme activity is implicated in a variety of diseases. Cardiac HDAC6 and HDAC8 enzyme activity induced by deoxycorticosterone acetate (DOCA) hypertension was attenuated by sodium valproate, a pan-HDAC inhibitor. H...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kee, Hae Jin, Ryu, Yuhee, Seok, Young Mi, Choi, Sin Young, Sun, Simei, Kim, Gwi Ran, Jeong, Myung Ho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570901/ https://www.ncbi.nlm.nih.gov/pubmed/31223486 http://dx.doi.org/10.1186/s40885-019-0118-8

Ejemplares similares

Class I histone deacetylase inhibitor MS-275 attenuates vasoconstriction and inflammation in angiotensin II-induced hypertension
por: Ryu, Yuhee, et al.
Publicado: (2019)

Histone deacetylase inhibitor LMK235 attenuates vascular constriction and aortic remodelling in hypertension
por: Choi, Sin Young, et al.
Publicado: (2019)

Gentisic acid prevents the transition from pressure overload-induced cardiac hypertrophy to heart failure
por: Sun, Simei, et al.
Publicado: (2019)

Gentisic acid attenuates pressure overload‐induced cardiac hypertrophy and fibrosis in mice through inhibition of the ERK1/2 pathway
por: Sun, Simei, et al.
Publicado: (2018)

Expression of Class I and Class II a/b Histone Deacetylase is Dysregulated in Hypertensive Animal Models
por: Kee, Hae Jin, et al.
Publicado: (2017)

Gallic Acid Reduces Blood Pressure and Attenuates Oxidative Stress and Cardiac Hypertrophy in Spontaneously Hypertensive Rats
por: Jin, Li, et al.
Publicado: (2017)

Piceatannol Attenuates Renal Fibrosis Induced by Unilateral Ureteral Obstruction via Downregulation of Histone Deacetylase 4/5 or p38-MAPK Signaling
por: Choi, Sin Young, et al.
Publicado: (2016)

Gallic acid attenuates calcium calmodulin‐dependent kinase II‐induced apoptosis in spontaneously hypertensive rats
por: Jin, Li, et al.
Publicado: (2017)

Gallic acid improves cardiac dysfunction and fibrosis in pressure overload-induced heart failure
por: Jin, Li, et al.
Publicado: (2018)

Gallic acid prevents isoproterenol-induced cardiac hypertrophy and fibrosis through regulation of JNK2 signaling and Smad3 binding activity
por: Ryu, Yuhee, et al.
Publicado: (2016)

Roles and Targets of Class I and IIa Histone Deacetylases in Cardiac Hypertrophy
por: Kee, Hae Jin, et al.
Publicado: (2011)

Histone deacetylase inhibitor, CG200745, attenuates cardiac hypertrophy and fibrosis in DOCA-induced hypertensive rats
por: Lee, Eunjo, et al.
Publicado: (2016)

Estrogen regulates histone deacetylases to prevent cardiac hypertrophy
por: Pedram, Ali, et al.
Publicado: (2013)

New Aspects of Vascular Calcification: Histone Deacetylases and Beyond
por: Kwon, Duk-Hwa, et al.
Publicado: (2017)

Mechanism of histone deacetylases in cardiac hypertrophy and its therapeutic inhibitors
por: Han, Yu, et al.
Publicado: (2022)

Role of histone deacetylase 2 and its posttranslational modifications in cardiac hypertrophy
por: Eom, Gwang Hyeon, et al.
Publicado: (2015)

Histone Deacetylase 3 and 4 Complex Stimulates the Transcriptional Activity of the Mineralocorticoid Receptor
por: Lee, Hae-Ahm, et al.
Publicado: (2015)

The role of histone deacetylase 4 during chondrocyte hypertrophy and endochondral bone development
por: Chen, Zhi, et al.
Publicado: (2020)

The Level of Histone Deacetylase 4 is Associated with Aging Cartilage Degeneration and Chondrocyte Hypertrophy
por: Dong, Zhengquan, et al.
Publicado: (2022)

Class I HDACs specifically regulate E‐cadherin expression in human renal epithelial cells
por: Choi, Sin Y., et al.
Publicado: (2016)

Histone Deacetylases and Histone Deacetylase Inhibitors in Neuroblastoma
por: Phimmachanh, Monica, et al.
Publicado: (2020)

MicroRNA-381 Regulates Chondrocyte Hypertrophy by Inhibiting Histone Deacetylase 4 Expression
por: Chen, Weishen, et al.
Publicado: (2016)

Repression of Transcriptional Activity of Forkhead Box O1 by Histone Deacetylase Inhibitors Ameliorates Hyperglycemia in Type 2 Diabetic Rats
por: Cho, Hyun Min, et al.
Publicado: (2018)

Effects of Angiotensin-(1-7) and Angiotensin II on Acetylcholine-Induced Vascular Relaxation in Spontaneously Hypertensive Rats
por: Zhang, Feng, et al.
Publicado: (2019)

MicroRNA-212-5p and its target PAFAH1B2 suppress vascular proliferation and contraction via the downregulation of RhoA
por: Kim, Gwi Ran, et al.
Publicado: (2021)

Dual Inhibitors Against Topoisomerases and Histone Deacetylases
por: Seo, Young Ho
Publicado: (2015)

Beyond Histone and Deacetylase: An Overview of Cytoplasmic Histone Deacetylases and Their Nonhistone Substrates
por: Yao, Ya-Li, et al.
Publicado: (2011)

Histone Deacetylases and Histone Deacetylase Inhibitors: Molecular Mechanisms of Action in Various Cancers
por: Sanaei, Masumeh, et al.
Publicado: (2019)

Histone Deacetylase HDT1 is Involved in Stem Vascular Development in Arabidopsis
por: Zhang, Yongzhuo, et al.
Publicado: (2019)

Histone Acetylation Level and Histone Acetyltransferase/Deacetylase Activity in Ejaculated Sperm from Normozoospermic Men
por: Kim, Jee Hyun, et al.
Publicado: (2014)

Histone Deacetylases and Their Regulatory MicroRNAs in Hepatocarcinogenesis
por: Kim, Hyung Seok, et al.
Publicado: (2015)

Targeted inhibition of histone deacetylase 6 in inflammatory diseases
por: Ran, Jie, et al.
Publicado: (2019)

Pressure Overload-Induced Cardiac Hypertrophy Response Requires Janus Kinase 2-Histone Deacetylase 2 Signaling
por: Ying, Huang, et al.
Publicado: (2014)

Histone Deacetylase Adaptation in Single Ventricle Heart Disease and a Young Animal Model of Right Ventricular Hypertrophy
por: Blakeslee, Weston W., et al.
Publicado: (2017)

Left ventricular hypertrophy and renin-angiotensin system blockade
por: Cowan, Brett R., et al.
Publicado: (2009)

An Interaction of Renin-Angiotensin and Kallikrein-Kinin Systems Contributes to Vascular Hypertrophy in Angiotensin II-Induced Hypertension: In Vivo and In Vitro Studies
por: Ceravolo, Graziela S., et al.
Publicado: (2014)

Epigenetic Targeting of Histone Deacetylases in Diagnostics and Treatment of Depression
por: Park, Hyun-Sun, et al.
Publicado: (2021)

Histone Deacetylase SIRT1, Smooth Muscle Cell Function, and Vascular Diseases
por: Wang, Fang, et al.
Publicado: (2020)

The microRNA miR‐134‐5p induces calcium deposition by inhibiting histone deacetylase 5 in vascular smooth muscle cells
por: Choe, Nakwon, et al.
Publicado: (2020)

Ligand-activated PPARδ inhibits angiotensin II-stimulated hypertrophy of vascular smooth muscle cells by targeting ROS
por: Kang, Eun Sil, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_thesdoevrho03jtgkf13l38k2j