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Modulation of phospho-proteins by interferon-alpha and valproic acid in acute myeloid leukemia

PURPOSE: Valproic acid (VPA) is suggested to be therapeutically beneficial in combination with interferon-alpha (IFNα) in various cancers. Therefore, we examined IFNα and VPA alone and in combinations in selected AML models, examining immune regulators and intracellular signaling mechanisms involved...

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Detalles Bibliográficos
Autores principales: Forthun, Rakel Brendsdal, Hellesøy, Monica, Sulen, André, Kopperud, Reidun Kristin, Sjøholt, Gry, Bruserud, Øystein, McCormack, Emmet, Gjertsen, Bjørn Tore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571093/
https://www.ncbi.nlm.nih.gov/pubmed/31111215
http://dx.doi.org/10.1007/s00432-019-02931-1