Inhibition of the Hypoxia-Inducible Factor 1α–Induced Cardiospecific HERNA1 Enhance-Templated RNA Protects From Heart Disease

BACKGROUND: Enhancers are genomic regulatory elements conferring spatiotemporal and signal-dependent control of gene expression. Recent evidence suggests that enhancers can generate noncoding enhancer RNAs, but their (patho)biological functions remain largely elusive. METHODS: We performed chromatin...

Descripción completa

Detalles Bibliográficos
Autores principales: Mirtschink, Peter, Bischof, Corinne, Pham, Minh-Duc, Sharma, Rahul, Khadayate, Sanjay, Rossi, Geetha, Fankhauser, Niklaus, Traub, Shuyang, Sossalla, Samuel, Hagag, Eman, Berthonneche, Corinne, Sarre, Alexandre, Stehr, Sebastian. N., Grote, Phillip, Pedrazzini, Thierry, Dimmeler, Stefanie, Krek, Wilhelm, Krishnan, Jaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571183/
https://www.ncbi.nlm.nih.gov/pubmed/30922078
http://dx.doi.org/10.1161/CIRCULATIONAHA.118.036769

Ejemplares similares

Ejemplares similares