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Pathogenesis of Thalassemia Major-associated Osteoporosis: A Review with Insights from Clinical Experience

Due to increasing life expectancy in thalassemia major (TM), osteoporosis is emerging as a significant problem. Its aetiology is multifactorial, culminating in increased bone resorption and impaired remodelling. Hypogonadism and marrow expansion seem to play an important role, but iron overload, def...

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Detalles Bibliográficos
Autores principales:	Gaudio, Agostino, Morabito, Nancy, Catalano, Antonino, Rapisarda, Rosario, Xourafa, Anastasia, Lasco, Antonino
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Galenos Publishing 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571534/ https://www.ncbi.nlm.nih.gov/pubmed/29991466 http://dx.doi.org/10.4274/jcrpe.galenos.2018.2018.0074

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