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Pathogenesis of Thalassemia Major-associated Osteoporosis: A Review with Insights from Clinical Experience
Due to increasing life expectancy in thalassemia major (TM), osteoporosis is emerging as a significant problem. Its aetiology is multifactorial, culminating in increased bone resorption and impaired remodelling. Hypogonadism and marrow expansion seem to play an important role, but iron overload, def...
Autores principales: | Gaudio, Agostino, Morabito, Nancy, Catalano, Antonino, Rapisarda, Rosario, Xourafa, Anastasia, Lasco, Antonino |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Galenos Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571534/ https://www.ncbi.nlm.nih.gov/pubmed/29991466 http://dx.doi.org/10.4274/jcrpe.galenos.2018.2018.0074 |
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