Cargando…

NMR-Based Metabolomic Approach Tracks Potential Serum Biomarkers of Disease Progression in Patients with Type 2 Diabetes Mellitus

Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by chronic hyperglycemia associated with alterations in carbohydrate, lipid, and protein metabolism. The prognosis of T2DM patients is highly dependent on the development of complications, and therefore the identification of bioma...

Descripción completa

Detalles Bibliográficos
Autores principales:	Del Coco, Laura, Vergara, Daniele, De Matteis, Serena, Mensà, Emanuela, Sabbatinelli, Jacopo, Prattichizzo, Francesco, Bonfigli, Anna Rita, Storci, Gianluca, Bravaccini, Sara, Pirini, Francesca, Ragusa, Andrea, Casadei-Gardini, Andrea, Bonafè, Massimiliano, Maffia, Michele, Fanizzi, Francesco Paolo, Olivieri, Fabiola, Giudetti, Anna Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571571/ https://www.ncbi.nlm.nih.gov/pubmed/31117294 http://dx.doi.org/10.3390/jcm8050720

Ejemplares similares

Response to: Letter to the Editor on “Bonafè M, Prattichizzo F, Giuliani A, Storci G, Sabbatinelli J, Olivieri F. Inflamm-aging: Why older men are the most susceptible to SARS-CoV-2 complicated outcomes. Cytokine Growth Factor Rev” by Eugenia Quiros-Roldan, Giorgio Biasiotto and Isabella Zanella
por: Prattichizzo, Francesco, et al.
Publicado: (2021)

Inflamm-aging: Why older men are the most susceptible to SARS-CoV-2 complicated outcomes
por: Bonafè, Massimiliano, et al.
Publicado: (2020)

Aberrant Metabolism in Hepatocellular Carcinoma Provides Diagnostic and Therapeutic Opportunities
por: De Matteis, Serena, et al.
Publicado: (2018)

Senescent macrophages in the human adipose tissue as a source of inflammaging
por: Matacchione, Giulia, et al.
Publicado: (2022)

(1)H-NMR Based Serum Metabolomics Highlights Different Specific Biomarkers between Early and Advanced Hepatocellular Carcinoma Stages
por: Casadei-Gardini, Andrea, et al.
Publicado: (2020)

Senescent Endothelial Cells Sustain Their Senescence-Associated Secretory Phenotype (SASP) through Enhanced Fatty Acid Oxidation
por: Giuliani, Angelica, et al.
Publicado: (2023)

Leukocyte telomere length and mortality risk in patients with type 2 diabetes
por: Bonfigli, Anna Rita, et al.
Publicado: (2016)

Long-term exposure of human endothelial cells to metformin modulates miRNAs and isomiRs
por: Giuliani, Angelica, et al.
Publicado: (2020)

Tackling the pillars of ageing to fight COVID-19
por: Prattichizzo, Francesco, et al.
Publicado: (2021)

Oxidative Molecular Mechanisms Underlying Liver Diseases: From Systems Biology to the Personalized Medicine
por: Vergara, Daniele, et al.
Publicado: (2019)

Extracellular vesicles circulating in young organisms promote healthy longevity
por: Prattichizzo, Francesco, et al.
Publicado: (2019)

Where Metabolism Meets Senescence: Focus on Endothelial Cells
por: Sabbatinelli, Jacopo, et al.
Publicado: (2019)

Senescence associated macrophages and “macroph-aging”: are they pieces of the same puzzle?
por: Prattichizzo, Francesco, et al.
Publicado: (2016)

Age-related M1/M2 phenotype changes in circulating monocytes from healthy/unhealthy individuals
por: Costantini, Andrea, et al.
Publicado: (2018)

The mitomiR/Bcl-2 axis affects mitochondrial function and autophagic vacuole formation in senescent endothelial cells
por: Giuliani, Angelica, et al.
Publicado: (2018)

Microbiota-Derived Metabolites in Tumor Progression and Metastasis
por: Rossi, Tania, et al.
Publicado: (2020)

Age-related modulation of plasmatic beta-Galactosidase activity in healthy subjects and in patients affected by T2DM
por: Spazzafumo, Liana, et al.
Publicado: (2017)

Extracellular vesicle-shuttled miRNAs: a critical appraisal of their potential as nano-diagnostics and nano-therapeutics in type 2 diabetes mellitus and its cardiovascular complications
por: Prattichizzo, Francesco, et al.
Publicado: (2021)

MiR-21-5p and miR-126a-3p levels in plasma and circulating angiogenic cells: relationship with type 2 diabetes complications
por: Olivieri, Fabiola, et al.
Publicado: (2015)

Androgen receptor in breast cancer: The “5W” questions
por: Ravaioli, Sara, et al.
Publicado: (2022)

The role of extracellular DNA in COVID-19: Clues from inflamm-aging
por: Storci, Gianluca, et al.
Publicado: (2021)

Epigenetic mechanisms of endothelial dysfunction in type 2 diabetes
por: Prattichizzo, Francesco, et al.
Publicado: (2015)

Randomized, Double-Blind, Placebo-Controlled Trial to Test the Effects of a Nutraceutical Combination Monacolin K-Free on the Lipid and Inflammatory Profile of Subjects with Hypercholesterolemia
por: Protic, Olga, et al.
Publicado: (2022)

Association of admission serum levels of neurofilament light chain and in-hospital mortality in geriatric patients with COVID-19
por: Marchegiani, Francesca, et al.
Publicado: (2022)

Circulating levels of AGEs and soluble RAGE isoforms are associated with all-cause mortality and development of cardiovascular complications in type 2 diabetes: a retrospective cohort study
por: Sabbatinelli, Jacopo, et al.
Publicado: (2022)

Blood Metabolite Profiling of Antarctic Expedition Members: An (1)H NMR Spectroscopy-Based Study
por: Del Coco, Laura, et al.
Publicado: (2023)

Small extracellular vesicles deliver miR-21 and miR-217 as pro-senescence effectors to endothelial cells
por: Mensà, Emanuela, et al.
Publicado: (2020)

Expanding Roles of De Novo Lipogenesis in Breast Cancer
por: Simeone, Pasquale, et al.
Publicado: (2021)

Replicative Senescence-Associated LINE1 Methylation and LINE1-Alu Expression Levels in Human Endothelial Cells
por: Ramini, Deborah, et al.
Publicado: (2022)

NMR-Based Metabolomics in Metal-Based Drug Research
por: De Castro, Federica, et al.
Publicado: (2019)

Circulating biomarkers of inflammaging as potential predictors of COVID-19 severe outcomes
por: Sabbatinelli, Jacopo, et al.
Publicado: (2022)

Modulation of soluble receptor for advanced glycation end-products (RAGE) isoforms and their ligands in healthy aging
por: Scavello, Francesco, et al.
Publicado: (2019)

Circulating PCSK9 as a prognostic biomarker of cardiovascular events in individuals with type 2 diabetes: evidence from a 16.8-year follow-up study
por: Ruscica, Massimiliano, et al.
Publicado: (2023)

The Association between Single Nucleotide Polymorphisms, including miR-499a Genetic Variants, and Dyslipidemia in Subjects Treated with Pharmacological or Phytochemical Lipid-Lowering Agents
por: Giuliani, Angelica, et al.
Publicado: (2022)

Composition and Statistical Analysis of Biophenols in Apulian Italian EVOOs
por: Ragusa, Andrea, et al.
Publicado: (2017)

(1)H NMR Spectroscopy and Multivariate Analysis of Monovarietal EVOOs as a Tool for Modulating Coratina-Based Blends
por: Del Coco, Laura, et al.
Publicado: (2014)

MiR-422a promotes adipogenesis via MeCP2 downregulation in human bone marrow mesenchymal stem cells
por: Giuliani, Angelica, et al.
Publicado: (2023)

Chronic Oleoylethanolamide Treatment Decreases Hepatic Triacylglycerol Level in Rat Liver by a PPARγ/SREBP-Mediated Suppression of Fatty Acid and Triacylglycerol Synthesis
por: Romano, Adele, et al.
Publicado: (2021)

Prognostic value of soluble ST2, high-sensitivity cardiac troponin, and NT-proBNP in type 2 diabetes: a 15-year retrospective study
por: Sabbatinelli, Jacopo, et al.
Publicado: (2022)

Routine laboratory parameters, including complete blood count, predict COVID-19 in-hospital mortality in geriatric patients
por: Olivieri, Fabiola, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_2kmffjk195j9clq87e66i4s073