In Silico Prediction of Plasma Concentrations of Fluconazole Capsules with Different Dissolution Profiles and Bioequivalence Study Using Population Simulation

A biowaiver is accepted by the Brazilian Health Surveillance Agency (ANVISA) for immediate-release solid oral products containing Biopharmaceutics Classification System (BCS) class I drugs showing rapid drug dissolution. This study aimed to simulate plasma concentrations of fluconazole capsules with...

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Detalles Bibliográficos
Autores principales: Duque, Marcelo Dutra, Silva, Daniela Amaral, Issa, Michele Georges, Porta, Valentina, Löbenberg, Raimar, Ferraz, Humberto Gomes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571621/
https://www.ncbi.nlm.nih.gov/pubmed/31060289
http://dx.doi.org/10.3390/pharmaceutics11050215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571621/
https://www.ncbi.nlm.nih.gov/pubmed/31060289
http://dx.doi.org/10.3390/pharmaceutics11050215

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