Cargando…

Mineralocorticoid Receptor May Regulate Glucose Homeostasis through the Induction of Interleukin-6 and Glucagon-Like peptide-1 in Pancreatic Islets

Because the renin-angiotensin-aldosterone system influences glucose homeostasis, the mineralocorticoid receptor (MR) signal in pancreatic islets may regulate insulin response upon glucose load. Glucagon-like peptide-1 (GLP-1) production is stimulated by interleukin-6 (IL-6) in pancreatic α-cells. To...

Descripción completa

Detalles Bibliográficos
Autores principales:	Goto, Rieko, Kondo, Tatsuya, Ono, Kaoru, Kitano, Sayaka, Miyakawa, Nobukazu, Watanabe, Takuro, Sakaguchi, Masaji, Sato, Miki, Igata, Motoyuki, Kawashima, Junji, Motoshima, Hiroyuki, Matsumura, Takeshi, Shimoda, Seiya, Araki, Eiichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571682/ https://www.ncbi.nlm.nih.gov/pubmed/31091693 http://dx.doi.org/10.3390/jcm8050674

Ejemplares similares

The Amount of Residual Incretin Regulates the Pancreatic β-cell Function and Glucose Homeostasis
por: Kondo, Tatsuya, et al.
Publicado: (2021)

Activation of heat shock response improves biomarkers of NAFLD in patients with metabolic diseases
por: Kondo, Tatsuya, et al.
Publicado: (2021)

Identification of microRNA that represses IRS-1 expression in liver
por: Ono, Kaoru, et al.
Publicado: (2018)

Effects of combination therapy with vildagliptin and valsartan in a mouse model of type 2 diabetes
por: Miyagawa, Katsutoshi, et al.
Publicado: (2013)

Activation of heat shock response to treat obese subjects with type 2 diabetes: a prospective, frequency-escalating, randomized, open-label, triple-arm trial
por: Kondo, Tatsuya, et al.
Publicado: (2016)

Mild Electrical Stimulation with Heat Shock Reduces Visceral Adiposity and Improves Metabolic Abnormalities in Subjects with Metabolic Syndrome or Type 2 Diabetes: Randomized Crossover Trials
por: Kondo, Tatsuya, et al.
Publicado: (2014)

Rapid and dramatic glucose‐lowering effect of bromocriptine in an inadequately controlled type 2 diabetes patient with prolactinoma
por: Igata, Motoyuki, et al.
Publicado: (2020)

The Role of Heat Shock Response in Insulin Resistance and Diabetes
por: Kondo, Tatsuya, et al.
Publicado: (2014)

Impacts of the 2016 Kumamoto Earthquake on glycemic control in patients with diabetes
por: Kondo, Tatsuya, et al.
Publicado: (2018)

Coexistence of resistance to thyroid hormone and papillary thyroid carcinoma
por: Igata, Motoyuki, et al.
Publicado: (2016)

Acetate alters expression of genes involved in beige adipogenesis in 3T3-L1 cells and obese KK-Ay mice
por: Hanatani, Satoko, et al.
Publicado: (2016)

Potential of a glucagon‐like peptide‐1 receptor/glucose‐dependent insulinotropic polypeptide receptor/glucagon receptor triagonist for the treatment of obesity and type 2 diabetes
por: Araki, Eiichi, et al.
Publicado: (2022)

Comparison of the efficacy of sitagliptin and glimepiride dose‐up in Japanese patients with type 2 diabetes poorly controlled by sitagliptin and glimepiride in combination
por: Shimoda, Seiya, et al.
Publicado: (2013)

The clinical course and pathophysiological investigation of adolescent gestational diabetes insipidus: a case report
por: Kondo, Tatsuya, et al.
Publicado: (2018)

Thiazolidinedione‐independent activation of peroxisome proliferator‐activated receptor γ is a potential target for diabetic macrovascular complications
por: Matsumura, Takeshi, et al.
Publicado: (2011)

Ectopic ACTH-producing neuroendocrine tumor occurring with large recurrent metastatic pheochromocytoma: a case report
por: Saishouji, Fumi, et al.
Publicado: (2022)

Ezetimibe improves glucose metabolism by ameliorating hepatic function in Japanese patients with type 2 diabetes
por: Ichimori, Shinji, et al.
Publicado: (2011)

Phosphatase protector alpha4 (α4) is involved in adipocyte maintenance and mitochondrial homeostasis through regulation of insulin signaling
por: Sakaguchi, Masaji, et al.
Publicado: (2022)

Association between circulating leukocyte subtype counts and carotid intima-media thickness in Japanese subjects with type 2 diabetes
por: Matsumura, Takeshi, et al.
Publicado: (2013)

New perspectives on insulin therapy
por: Araki, Eiichi, et al.
Publicado: (2020)

A 1‐year, prospective, observational study of Japanese outpatients with type 1 and type 2 diabetes switching from insulin glargine or detemir to insulin degludec in basal–bolus insulin therapy (Kumamoto Insulin Degludec Observational study)
por: Shimoda, Seiya, et al.
Publicado: (2016)

Low glucose induces mitochondrial reactive oxygen species via fatty acid oxidation in bovine aortic endothelial cells
por: Kajihara, Nobuhiro, et al.
Publicado: (2017)

Hyperthermia With Mild Electrical Stimulation Protects Pancreatic β-Cells From Cell Stresses and Apoptosis
por: Kondo, Tatsuya, et al.
Publicado: (2012)

Intra-islet glucagon secretion and action in the regulation of glucose homeostasis
por: Wang, Qinghua, et al.
Publicado: (2013)

Melatonin and Pancreatic Islets: Interrelationships between Melatonin, Insulin and Glucagon
por: Peschke, Elmar, et al.
Publicado: (2013)

In vivo studies of glucagon secretion by human islets transplanted in mice
por: Tellez, Krissie, et al.
Publicado: (2020)

Small molecule glucagon release inhibitors with activity in human islets
por: Kalwat, Michael A., et al.
Publicado: (2023)

Short-Term Cost-Effectiveness of Switching to Insulin Degludec in Japanese Patients with Type 2 Diabetes Receiving Basal–Bolus Therapy
por: Langer, Jakob, et al.
Publicado: (2019)

Predictors of coronary heart disease in Japanese patients with type 2 diabetes: Screening for coronary artery stenosis using multidetector computed tomography
por: Nishioka, Hiroko, et al.
Publicado: (2010)

A rare case showing subacute thyroiditis-like symptoms with amyloid goiter after anti-tumor necrosis factor therapy
por: Kawashima, Junji, et al.
Publicado: (2015)

Mineralocorticoid hypertension
por: Gupta, Vishal
Publicado: (2011)

Expression of genes encoding mineralocorticoid biosynthetic enzymes and the mineralocorticoid receptor, and levels of mineralocorticoids in the bovine follicle and corpus luteum
por: MUKANGWA, Memory, et al.
Publicado: (2019)

Hyperglycemia Induces Cellular Hypoxia through Production of Mitochondrial ROS Followed by Suppression of Aquaporin-1
por: Sada, Kiminori, et al.
Publicado: (2016)

Taking Aim at Islet Hormones With GLP-1: Is Insulin or Glucagon the Better Target?
por: D'Alessio, David A.
Publicado: (2010)

A Variation on the Theme: SGLT2 Inhibition and Glucagon Secretion in Human Islets
por: Hodson, David J., et al.
Publicado: (2020)

Evidence for the existence and potential roles of intra-islet glucagon-like peptide-1
por: Campbell, Scott A., et al.
Publicado: (2021)

ULTRASTRUCTURE OF THE A-CELLS OF CAT ISLETS OF LANGERHANS FOLLOWING SYMPATHETIC STIMULATION OF GLUCAGON SECRETION
por: Esterhuizen, A. C., et al.
Publicado: (1970)

Puzzling About Partial Glucagon Responses to Hypoglycemia in Intrahepatic Islet Recipients: Missing Pieces
por: Robertson, R. Paul
Publicado: (2015)

Abnormal regulation of glucagon secretion by human islet alpha cells in the absence of beta cells
por: Liu, Wei, et al.
Publicado: (2019)

A microfluidic system for monitoring glucagon secretion from human pancreatic islets of Langerhans
por: Eaton, Wesley J., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_4uq0lg77g1qt6683g6u1j3da7i