Synthesis, Biological Evaluation, and In Silico Studies of Novel Aminated Xanthones as Potential p53-Activating Agents

Xanthone scaffold has been regarded as an attractive chemical tool in the search for bioactive molecules with antitumor activity, and in particular two xanthone derivatives, 12-hydroxy-2,2-dimethyl-3,4-dihydro-2H,6H-pyrano [3,2-b]xanthen-6-one (4) and 3,4-dimethoxy-9-oxo-9H-xanthene-1-carbaldehyde (...

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Detalles Bibliográficos
Autores principales: Lemos, Agostinho, Gomes, Ana Sara, Loureiro, Joana B., Brandão, Pedro, Palmeira, Andreia, Pinto, Madalena M. M., Saraiva, Lucília, Sousa, Maria Emília
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571851/
https://www.ncbi.nlm.nih.gov/pubmed/31121972
http://dx.doi.org/10.3390/molecules24101975

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571851/
https://www.ncbi.nlm.nih.gov/pubmed/31121972
http://dx.doi.org/10.3390/molecules24101975

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