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Bile acids inhibit human purinergic receptor P2X4 in a heterologous expression system

We recently demonstrated that bile acids, especially tauro-deoxycholic acid (t-DCA), modify the function of the acid-sensing ion channel ASIC1a and other members of the epithelial sodium channel (ENaC)/degenerin (DEG) ion channel family. Surprisingly, ASIC1 shares a high degree of structural similar...

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Detalles Bibliográficos
Autores principales:	Ilyaskin, Alexandr V., Sure, Florian, Nesterov, Viatcheslav, Haerteis, Silke, Korbmacher, Christoph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572003/ https://www.ncbi.nlm.nih.gov/pubmed/30988062 http://dx.doi.org/10.1085/jgp.201812291

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