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Current Mechanistic and Pharmacodynamic Understanding of Melanocortin-4 Receptor Activation

In this work we summarize our understanding of melanocortin 4 receptor (MC4R) pathway activation, aiming to define a safe and effective therapeutic targeting strategy for the MC4R. Delineation of cellular MC4R pathways has provided evidence for distinct MC4R signaling events characterized by unique...

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Detalles Bibliográficos
Autores principales:	Sharma, Shubh, Garfield, Alastair S., Shah, Bhavik, Kleyn, Patrick, Ichetovkin, Ilia, Moeller, Ida Hatoum, Mowrey, William R., Van der Ploeg, Lex H.T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572030/ https://www.ncbi.nlm.nih.gov/pubmed/31100979 http://dx.doi.org/10.3390/molecules24101892

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