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Aza-Amino Acids Disrupt β-Sheet Secondary Structures

Cα to N substitution in aza-amino acids imposes local conformational constraints, changes in hydrogen bonding properties, and leads to adaptive chirality at the nitrogen atom. These properties can be exploited in mimicry and stabilization of peptide secondary structures and self-assembly. Here, the...

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Detalles Bibliográficos
Autores principales:	McMechen, Michael A., Willis, Evan L., Gourville, Preston C., Proulx, Caroline
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572070/ https://www.ncbi.nlm.nih.gov/pubmed/31109055 http://dx.doi.org/10.3390/molecules24101919

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