Ethyl Pyruvate Directly Attenuates Active Secretion of HMGB1 in Proximal Tubular Cells via Induction of Heme Oxygenase-1

Renal ischemia reperfusion (IR) is a main cause of acute kidney injury leading to high morbidity and mortality during postoperative periods. This study investigated whether ethyl pyruvate (EP) protects the kidney against renal IR injury. Male C57BL/6 mice were treated with vehicle or EP (40 mg/kg) 1...

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Detalles Bibliográficos
Autores principales: Seo, Min Suk, Kim, Hye Jung, Kim, Hwajin, Park, Sang Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572201/
https://www.ncbi.nlm.nih.gov/pubmed/31072024
http://dx.doi.org/10.3390/jcm8050629

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