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Glucocorticoid Receptor Modulates EGFR Feedback upon Acquisition of Resistance to Monoclonal Antibodies

Evidences of a crosstalk between Epidermal Growth Factor Receptor (EGFR) and Glucocorticoid Receptor (GR) has been reported, ranging from the modulation of receptor levels or GR mediated transcriptional repression of EGFR target genes, with modifications of epigenetic markers. The present study focu...

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Detalles Bibliográficos
Autores principales: Gelfo, Valerio, Pontis, Francesca, Mazzeschi, Martina, Sgarzi, Michela, Mazzarini, Maria, Solmi, Rossella, D’Uva, Gabriele, Lauriola, Mattia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572202/
https://www.ncbi.nlm.nih.gov/pubmed/31052457
http://dx.doi.org/10.3390/jcm8050600