Cargando…

Reverse Transcriptase Inhibitors Nanosystems Designed for Drug Stability and Controlled Delivery

An in-depth analysis of nanotechnology applications for the improvement of solubility, distribution, bioavailability and stability of reverse transcriptase inhibitors is reported. Current clinically used nucleoside and non-nucleoside agents, included in combination therapies, were examined in the pr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Grande, Fedora, Ioele, Giuseppina, Occhiuzzi, Maria Antonietta, De Luca, Michele, Mazzotta, Elisabetta, Ragno, Gaetano, Garofalo, Antonio, Muzzalupo, Rita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572254/ https://www.ncbi.nlm.nih.gov/pubmed/31035595 http://dx.doi.org/10.3390/pharmaceutics11050197

Ejemplares similares

Gel Formulation of Nabumetone and a Newly Synthesized Analog: Microemulsion as a Photoprotective Topical Delivery System
por: Grande, Fedora, et al.
Publicado: (2020)

Use of Pluronic Surfactants in Gel Formulations of Photosensitive 1,4-Dihydropyridine Derivatives: A Potential Approach in the Treatment of Neuropathic Pain
por: Ioele, Giuseppina, et al.
Publicado: (2021)

Photodegradation of Anti-Inflammatory Drugs: Stability Tests and Lipid Nanocarriers for Their Photoprotection
por: Ioele, Giuseppina, et al.
Publicado: (2021)

Anticancer Drugs: Recent Strategies to Improve Stability Profile, Pharmacokinetic and Pharmacodynamic Properties
por: Ioele, Giuseppina, et al.
Publicado: (2022)

Interaction of letrozole and its degradation products with aromatase: chemometric assessment of kinetics and structure-based binding validation
por: De Luca, Michele, et al.
Publicado: (2022)

Multivariate Curve Resolution Methodology Applied to the ATR-FTIR Data for Adulteration Assessment of Virgin Coconut Oil
por: De Luca, Michele, et al.
Publicado: (2023)

Toward Multitasking Pharmacological COX-Targeting Agents: Non-Steroidal Anti-Inflammatory Prodrugs with Antiproliferative Effects
por: Grande, Fedora, et al.
Publicado: (2021)

Polyphenols from Citrus Tacle(®) Extract Endowed with HMGCR Inhibitory Activity: An Antihypercholesterolemia Natural Remedy
por: Grande, Fedora, et al.
Publicado: (2021)

CCR5/CXCR4 Dual Antagonism for the Improvement of HIV Infection Therapy
por: Grande, Fedora, et al.
Publicado: (2019)

A New Generation of Dihydropyridine Calcium Channel Blockers: Photostabilization of Liquid Formulations Using Nonionic Surfactants
por: Ioele, Giuseppina, et al.
Publicado: (2019)

Identification by Molecular Docking of Homoisoflavones from Leopoldia comosa as Ligands of Estrogen Receptors
por: Grande, Fedora, et al.
Publicado: (2018)

Photosensitive drugs: a review on their photoprotection by liposomes and cyclodextrins
por: Ioele, Giuseppina, et al.
Publicado: (2017)

1,4-Dihydropyridine Antihypertensive Drugs: Recent Advances in Photostabilization Strategies
por: De Luca, Michele, et al.
Publicado: (2019)

Optimization of wavelength range and data interval in chemometric analysis of complex pharmaceutical mixtures()
por: De Luca, Michele, et al.
Publicado: (2016)

Thermo-Sensitive Vesicles in Controlled Drug Delivery for Chemotherapy
por: Mazzotta, Elisabetta, et al.
Publicado: (2018)

Actively Targeted and Redox Responsive Delivery of Anticancer Drug by Chitosan Nanoparticles
por: Mazzotta, Elisabetta, et al.
Publicado: (2019)

Evaluation of human breastmilk adulteration by combining Fourier transform infrared spectroscopy and partial least square modeling
por: De Luca, Michele, et al.
Publicado: (2019)

Control of the Verticillium Wilt on Tomato Plants by Means of Olive Leaf Extracts Loaded on Chitosan Nanoparticles
por: Mazzotta, Elisabetta, et al.
Publicado: (2022)

Computational Approaches for the Discovery of GPER Targeting Compounds
por: Grande, Fedora, et al.
Publicado: (2020)

New Nanomaterials with Intrinsic Antioxidant Activity by Surface Functionalization of Niosomes with Natural Phenolic Acids
por: Mazzotta, Elisabetta, et al.
Publicado: (2021)

Lidosomes: Innovative Vesicular Systems Prepared from Lidocaine Surfadrug
por: Romeo, Martina, et al.
Publicado: (2022)

Direct and Reverse Pluronic Micelles: Design and Characterization of Promising Drug Delivery Nanosystems
por: Naharros-Molinero, Almudena, et al.
Publicado: (2022)

Design of Nanosystems for the Delivery of Quorum Sensing Inhibitors: A Preliminary Study
por: Hallan, Supandeep Singh, et al.
Publicado: (2020)

Identification of Pinosylvin in Pinus nigra subsp. laricio: A Naturally Occurring Stilbenoid Suppressing LPS-Induced Expression of Pro-Inflammatory Cytokines and Mediators and Inhibiting the JAK/STAT Signaling Pathway
por: Perri, Maria Rosaria, et al.
Publicado: (2023)

Lavandula angustifolia mill. (Lamiaceae) ethanol extract and its main constituents as promising agents for the treatment of metabolic disorders: chemical profile, in vitro biological studies, and molecular docking
por: Tundis, Rosa, et al.
Publicado: (2023)

Picomolar inhibitor of reverse transcriptase featuring significantly improved metabolic stability
por: Sang, Ya-Li, et al.
Publicado: (2023)

A reverse transcriptase ribozyme
por: Samanta, Biswajit, et al.
Publicado: (2017)

Reverse transcriptase activity in psoriatic lesions: effects of reverse transcriptase inhibitors on keratinocyte proliferation and differentiation
por: Molès, Jean-Pierre, et al.
Publicado: (2009)

Nanosystems as Vehicles for the Delivery of Antimicrobial Peptides (AMPs)
por: Martin-Serrano, Ángela, et al.
Publicado: (2019)

The Potential of Drug Delivery Nanosystems for Sepsis Treatment
por: Shi, Yi, et al.
Publicado: (2021)

Micro/Nanosystems for Magnetic Targeted Delivery of Bioagents
por: Garello, Francesca, et al.
Publicado: (2022)

Usefulness of Immunological Detection of the Human Telomerase Reverse Transcriptase
por: Volpi, Annalisa, et al.
Publicado: (2005)

Architecture of an HIV-1 reverse transcriptase initiation complex
por: Larsen, Kevin P., et al.
Publicado: (2018)

Low rates of nucleoside reverse transcriptase inhibitor and nonnucleoside reverse transcriptase inhibitor drug resistance in Botswana
por: Moyo, Sikhulile, et al.
Publicado: (2019)

Lipid-Based Nanosystems as a Tool to Overcome Skin Barrier
por: Sguizzato, Maddalena, et al.
Publicado: (2021)

Telomerase reverse transcriptase and neurodegenerative diseases
por: Yu, Xin, et al.
Publicado: (2023)

Reverse transcriptases prime DNA synthesis
por: Zabrady, Matej, et al.
Publicado: (2023)

Effect of reverse transcriptase inhibitors on LINE-1 and Ty1 reverse transcriptase activities and on LINE-1 retrotransposition
por: Dai, Lixin, et al.
Publicado: (2011)

Novel lentiviral vectors with mutated reverse transcriptase for mRNA delivery of TALE nucleases
por: Mock, Ulrike, et al.
Publicado: (2014)

Quantitative Evaluation of Very Low Levels of HIV-1 Reverse Transcriptase by a Novel Highly Sensitive RT-qPCR Assay
por: Marino-Merlo, Francesca, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_6hm99hf55774m5978npci9tuob