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Threads Made with Blended Biopolymers: Mechanical, Physical and Biological Features

Poly (Lactic Acid), PLA, and Poly (ε-CaproLactone), PCL, compatibilized with Ethyl Ester l-Lysine Triisocyanate (LTI) can be employed as biomaterials. We mixed PLA with PCL and LTI in a twin extruder and by a melt spinning process obtained threads with an average diameter of about 0.3 mm. In order t...

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Detalles Bibliográficos
Autores principales: Visco, Annamaria, Scolaro, Cristina, Giamporcaro, Alberto, De Caro, Salvatore, Tranquillo, Elisabetta, Catauro, Michelina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572296/
https://www.ncbi.nlm.nih.gov/pubmed/31108907
http://dx.doi.org/10.3390/polym11050901
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author Visco, Annamaria
Scolaro, Cristina
Giamporcaro, Alberto
De Caro, Salvatore
Tranquillo, Elisabetta
Catauro, Michelina
author_facet Visco, Annamaria
Scolaro, Cristina
Giamporcaro, Alberto
De Caro, Salvatore
Tranquillo, Elisabetta
Catauro, Michelina
author_sort Visco, Annamaria
collection PubMed
description Poly (Lactic Acid), PLA, and Poly (ε-CaproLactone), PCL, compatibilized with Ethyl Ester l-Lysine Triisocyanate (LTI) can be employed as biomaterials. We mixed PLA with PCL and LTI in a twin extruder and by a melt spinning process obtained threads with an average diameter of about 0.3 mm. In order to study the possible application of these threads, mechanical tensile (with the calorimetric and morphological investigations) and biological tests were performed. The results highlighted these biopolymers as promising materials for sutures since they can be rigid and elastic (especially by increasing the PCL amount in the blend), and they are bioactive, able to inhibit bacterial growth. This paper represents a starting point to optimize the blend composition for biomedical suture application.
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spelling pubmed-65722962019-06-18 Threads Made with Blended Biopolymers: Mechanical, Physical and Biological Features Visco, Annamaria Scolaro, Cristina Giamporcaro, Alberto De Caro, Salvatore Tranquillo, Elisabetta Catauro, Michelina Polymers (Basel) Article Poly (Lactic Acid), PLA, and Poly (ε-CaproLactone), PCL, compatibilized with Ethyl Ester l-Lysine Triisocyanate (LTI) can be employed as biomaterials. We mixed PLA with PCL and LTI in a twin extruder and by a melt spinning process obtained threads with an average diameter of about 0.3 mm. In order to study the possible application of these threads, mechanical tensile (with the calorimetric and morphological investigations) and biological tests were performed. The results highlighted these biopolymers as promising materials for sutures since they can be rigid and elastic (especially by increasing the PCL amount in the blend), and they are bioactive, able to inhibit bacterial growth. This paper represents a starting point to optimize the blend composition for biomedical suture application. MDPI 2019-05-17 /pmc/articles/PMC6572296/ /pubmed/31108907 http://dx.doi.org/10.3390/polym11050901 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Visco, Annamaria
Scolaro, Cristina
Giamporcaro, Alberto
De Caro, Salvatore
Tranquillo, Elisabetta
Catauro, Michelina
Threads Made with Blended Biopolymers: Mechanical, Physical and Biological Features
title Threads Made with Blended Biopolymers: Mechanical, Physical and Biological Features
title_full Threads Made with Blended Biopolymers: Mechanical, Physical and Biological Features
title_fullStr Threads Made with Blended Biopolymers: Mechanical, Physical and Biological Features
title_full_unstemmed Threads Made with Blended Biopolymers: Mechanical, Physical and Biological Features
title_short Threads Made with Blended Biopolymers: Mechanical, Physical and Biological Features
title_sort threads made with blended biopolymers: mechanical, physical and biological features
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572296/
https://www.ncbi.nlm.nih.gov/pubmed/31108907
http://dx.doi.org/10.3390/polym11050901
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