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Threads Made with Blended Biopolymers: Mechanical, Physical and Biological Features
Poly (Lactic Acid), PLA, and Poly (ε-CaproLactone), PCL, compatibilized with Ethyl Ester l-Lysine Triisocyanate (LTI) can be employed as biomaterials. We mixed PLA with PCL and LTI in a twin extruder and by a melt spinning process obtained threads with an average diameter of about 0.3 mm. In order t...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572296/ https://www.ncbi.nlm.nih.gov/pubmed/31108907 http://dx.doi.org/10.3390/polym11050901 |
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author | Visco, Annamaria Scolaro, Cristina Giamporcaro, Alberto De Caro, Salvatore Tranquillo, Elisabetta Catauro, Michelina |
author_facet | Visco, Annamaria Scolaro, Cristina Giamporcaro, Alberto De Caro, Salvatore Tranquillo, Elisabetta Catauro, Michelina |
author_sort | Visco, Annamaria |
collection | PubMed |
description | Poly (Lactic Acid), PLA, and Poly (ε-CaproLactone), PCL, compatibilized with Ethyl Ester l-Lysine Triisocyanate (LTI) can be employed as biomaterials. We mixed PLA with PCL and LTI in a twin extruder and by a melt spinning process obtained threads with an average diameter of about 0.3 mm. In order to study the possible application of these threads, mechanical tensile (with the calorimetric and morphological investigations) and biological tests were performed. The results highlighted these biopolymers as promising materials for sutures since they can be rigid and elastic (especially by increasing the PCL amount in the blend), and they are bioactive, able to inhibit bacterial growth. This paper represents a starting point to optimize the blend composition for biomedical suture application. |
format | Online Article Text |
id | pubmed-6572296 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-65722962019-06-18 Threads Made with Blended Biopolymers: Mechanical, Physical and Biological Features Visco, Annamaria Scolaro, Cristina Giamporcaro, Alberto De Caro, Salvatore Tranquillo, Elisabetta Catauro, Michelina Polymers (Basel) Article Poly (Lactic Acid), PLA, and Poly (ε-CaproLactone), PCL, compatibilized with Ethyl Ester l-Lysine Triisocyanate (LTI) can be employed as biomaterials. We mixed PLA with PCL and LTI in a twin extruder and by a melt spinning process obtained threads with an average diameter of about 0.3 mm. In order to study the possible application of these threads, mechanical tensile (with the calorimetric and morphological investigations) and biological tests were performed. The results highlighted these biopolymers as promising materials for sutures since they can be rigid and elastic (especially by increasing the PCL amount in the blend), and they are bioactive, able to inhibit bacterial growth. This paper represents a starting point to optimize the blend composition for biomedical suture application. MDPI 2019-05-17 /pmc/articles/PMC6572296/ /pubmed/31108907 http://dx.doi.org/10.3390/polym11050901 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Visco, Annamaria Scolaro, Cristina Giamporcaro, Alberto De Caro, Salvatore Tranquillo, Elisabetta Catauro, Michelina Threads Made with Blended Biopolymers: Mechanical, Physical and Biological Features |
title | Threads Made with Blended Biopolymers: Mechanical, Physical and Biological Features |
title_full | Threads Made with Blended Biopolymers: Mechanical, Physical and Biological Features |
title_fullStr | Threads Made with Blended Biopolymers: Mechanical, Physical and Biological Features |
title_full_unstemmed | Threads Made with Blended Biopolymers: Mechanical, Physical and Biological Features |
title_short | Threads Made with Blended Biopolymers: Mechanical, Physical and Biological Features |
title_sort | threads made with blended biopolymers: mechanical, physical and biological features |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572296/ https://www.ncbi.nlm.nih.gov/pubmed/31108907 http://dx.doi.org/10.3390/polym11050901 |
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