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Synthesis and Cytotoxic Evaluation of 3-Methylidenechroman-4-ones

In the search for new anticancer agents, a library of variously substituted 3-methylidenechroman-4-ones was synthesized using Horner–Wadsworth–Emmons methodology. Acylation of diethyl methylphosphonate with selected ethyl salicylates furnished 3-diethoxyphosphorylchromen-4-ones which were next used...

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Detalles Bibliográficos
Autores principales: Kędzia, Jacek, Bartosik, Tomasz, Drogosz, Joanna, Janecka, Anna, Krajewska, Urszula, Janecki, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572547/
https://www.ncbi.nlm.nih.gov/pubmed/31096601
http://dx.doi.org/10.3390/molecules24101868