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Amantadine Combines Astroglial System Xc(−) Activation with Glutamate/NMDA Receptor Inhibition

A glutamate/NMDA receptor (NMDA-R) antagonist, amantadine (AMA) exhibits a broad spectrum of clinically important properties, including antiviral, antiparkinsonian, neuroprotective, neuro-reparative and cognitive-enhancing effects. However, both clinical and pre-clinical studies have demonstrated th...

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Detalles Bibliográficos
Autores principales: Nakano, Tomosuke, Hasegawa, Toshiki, Suzuki, Dai, Motomura, Eishi, Okada, Motohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572554/
https://www.ncbi.nlm.nih.gov/pubmed/31108896
http://dx.doi.org/10.3390/biom9050191

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