Cargando…

Effects of MTHFR and ABCC2 gene polymorphisms on antiepileptic drug responsiveness in Jordanian epileptic patients

BACKGROUND: Epilepsy is one of the most common neurological diseases with unclear etiology where its genetic background and treatment regime still need further exploration. OBJECTIVES: This study designed to evaluate the pharmacogenomics of MTHFR and ABCC2 genes, and their association with epilepsy...

Descripción completa

Detalles Bibliográficos
Autores principales:	AL-Eitan, Laith N, Al-Dalalah, Islam M, Mustafa, Mohamed M, Alghamdi, Mansour A, Elshammari, Afrah K, Khreisat, Wael H, Aljamal, Hanan A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572658/ https://www.ncbi.nlm.nih.gov/pubmed/31354331 http://dx.doi.org/10.2147/PGPM.S211490

Ejemplares similares

Genetic Association of Epilepsy and Anti-Epileptic Drugs Treatment in Jordanian Patients
por: AL-Eitan, Laith N, et al.
Publicado: (2020)

The Impact of Potassium Channel Gene Polymorphisms on Antiepileptic Drug Responsiveness in Arab Patients with Epilepsy
por: AL-Eitan, Laith N., et al.
Publicado: (2018)

Genetic polymorphisms of CYP3A5, CHRM2, and ZNF498 and their association with epilepsy susceptibility: a pharmacogenetic and case–control study
por: AL-Eitan, Laith N, et al.
Publicado: (2019)

Effects of GRM4, SCN2A and SCN3B polymorphisms on antiepileptic drugs responsiveness and epilepsy susceptibility
por: AL-Eitan, Laith N., et al.
Publicado: (2019)

Genetic predisposition of alopecia areata in jordanians: A case-control study
por: AL-Eitan, Laith N., et al.
Publicado: (2022)

Genetic Association between Interleukin Genes and Alopecia Areata in Jordanian Patients
por: Eitan, Laith N. AL, et al.
Publicado: (2022)

SCN1A polymorphisms influence the antiepileptic drugs responsiveness in Jordanian epileptic patients
por: Abduljabbar, Rami, et al.
Publicado: (2023)

Candidate Gene Analysis Of Alopecia Areata In Jordanian Population Of Arab Descent: A Case–Control Study
por: AL-Eitan, Laith N, et al.
Publicado: (2019)

Impact of MTHFR (C677T) gene polymorphism on antiepileptic drug monotherapy in North Indian epileptic population
por: Munisamy, Murali, et al.
Publicado: (2015)

Application of Gas Chromatography–Mass Spectrometry for the Identification and Quantitation of Three Common Synthetic Cannabinoids in Seized Materials from the Jordanian Market
por: AL-Eitan, Laith N., et al.
Publicado: (2020)

Identification and Characterization of BTD Gene Mutations in Jordanian Children with Biotinidase Deficiency
por: AL-Eitan, Laith N., et al.
Publicado: (2020)

Association of CYP gene polymorphisms with breast cancer risk and prognostic factors in the Jordanian population
por: AL-Eitan, Laith N., et al.
Publicado: (2019)

Genetic association of XRCC5 gene polymorphisms with breast cancer among Jordanian women
por: AL-Eitan, Laith N, et al.
Publicado: (2019)

Genetic Association of SH2B1 Gene Polymorphisms in Jordanian Arab Patients with Type 2 Diabetes Mellitus
por: AL-Eitan, Laith N, et al.
Publicado: (2020)

Association Of GSTM1, GSTT1 And GSTP1 Polymorphisms With Breast Cancer Among Jordanian Women
por: AL-Eitan, Laith N, et al.
Publicado: (2019)

Genetic association of IL2RA, IL17RA, IL23R, and IL31RA single nucleotide polymorphisms with alopecia areata
por: Alghamdi, Mansour A., et al.
Publicado: (2022)

Role of Four ABC Transporter Genes in Pharmacogenetic Susceptibility to Breast Cancer in Jordanian Patients
por: AL-Eitan, Laith N., et al.
Publicado: (2019)

MTHFR gene polymorphisms in hypothyroidism and hyperthyroidism among Jordanian females
por: Abu-Hassan, Diala W., et al.
Publicado: (2019)

Influence of SH2B3, MTHFD1L, GGCX, and ITGB3 Gene Polymorphisms on theVariability on Warfarin Dosage Requirements and Susceptibility to CVD in the Jordanian Population
por: AL-Eitan, Laith N., et al.
Publicado: (2020)

Variants in CDHR3, CACNAC1, and LTA Genes Predisposing Sensitivity and Response to Warfarin in Patients with Cardiovascular Disease
por: Alghamdi, Mansour A, et al.
Publicado: (2021)

Correlation between Candidate Single Nucleotide Variants and Several Clinicopathological Risk Factors Related to Breast Cancer in Jordanian Women: A Genotype-Phenotype Study
por: AL-Eitan, Laith N., et al.
Publicado: (2019)

Association of toll-like receptor 4, 5 and 10 polymorphisms with Helicobacter pylori-positive peptic ulcer disease in a center in Jordan
por: AL-Eitan, Laith, et al.
Publicado: (2021)

Gas chromatographic–mass spectrometric analysis of sunscreens and their effects on mice liver and kidney enzyme function
por: AL-Eitan, Laith N, et al.
Publicado: (2018)

Impact of PCSK9, WDR12, CDKN2A, and CXCL12 Polymorphisms in Jordanian Cardiovascular Patients on Warfarin Responsiveness and Sensitivity
por: Ibdah, Rasheed K, et al.
Publicado: (2021)

Patterns of antiepileptic drugs use in epileptic pediatric patients in Jordan
por: Albsoul-Younes, Abla, et al.
Publicado: (2016)

The Number of Roots and Canals in the Maxillary Second Premolars in a Group of Jordanian Population
por: Al-Ghananeem, Muna M. F., et al.
Publicado: (2014)

Fitness Characteristics of Jordanian Emergency Medical Technicians
por: Al-Yousef, Hani Najeh Mansour, et al.
Publicado: (2019)

Effects of coagulation factor VII polymorphisms on warfarin sensitivity and responsiveness in Jordanian cardiovascular patients during the initiation and maintenance phases of warfarin therapy
por: AL-Eitan, Laith N, et al.
Publicado: (2019)

Family and case–control genetic study of MSX1 polymorphisms in peg-shaped teeth Jordanian population
por: Alkhatib, Rami, et al.
Publicado: (2022)

Custom genotyping for substance addiction susceptibility genes in Jordanians of Arab descent
por: AL-Eitan, Laith N, et al.
Publicado: (2012)

Association of Multiple Sclerosis Phenotypes with Single Nucleotide Polymorphisms of IL7R, LAG3, and CD40 Genes in a Jordanian Population: A Genotype-Phenotype Study
por: AL-Eitan, Laith, et al.
Publicado: (2020)

The Association of IL-1 and HRAS Gene Polymorphisms with Breast Cancer Susceptibility in a Jordanian Population of Arab Descent: A Genotype–Phenotype Study
por: AL-Eitan, Laith N., et al.
Publicado: (2020)

Impact of CYP2C9 and VKORC1 Polymorphisms on Warfarin Sensitivity and Responsiveness in Jordanian Cardiovascular Patients during the Initiation Therapy
por: AL-Eitan, Laith N., et al.
Publicado: (2018)

Genetic Analysis Of ABCA1 Gene Of Primary Glaucoma In Jordanian Arab Population
por: Alkhatib, Rami, et al.
Publicado: (2019)

The Associations of Common Genetic Susceptibility Variants with Breast Cancer in Jordanian Arabs: A Case-Control Study
por: AL-Eitan, Laith N, et al.
Publicado: (2020)

Predictors of Dehydration Following Adenotonsillectomy in Jordanian Pediatric Cases
por: Khasawneh, Laith, et al.
Publicado: (2022)

Impact of a variable number tandem repeat in the CYP2C9 promoter on warfarin sensitivity and responsiveness in Jordanians with cardiovascular disease
por: AL-Eitan, Laith N, et al.
Publicado: (2019)

Prevalence and Multiplicity of Thrombophilia Genetic Polymorphisms of FV, MTHFR, FII, and PAI-I: A Cross-Sectional Study on a Healthy Jordanian Population
por: Al-Zoubi, Nabil, et al.
Publicado: (2021)

Effect of MEF2A and SLC22A3-LPAL2-LPA gene polymorphisms on warfarin sensitivity and responsiveness in Jordanian cardiovascular patients
por: AL-Eitan, Laith N., et al.
Publicado: (2023)

Antiepileptic drug-induced psychosis associated with MTHFR C677T: a case report
por: Shimura, Masaru, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_08nj51al075etbotb9kt5kmcfe