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Bulged and Canonical G-Quadruplex Conformations Determine NDPK Binding Specificity
Guanine-rich DNA strands can adopt tertiary structures known as G-quadruplexes (G4s) that form when Hoogsteen base-paired guanines assemble as planar stacks, stabilized by a central cation like K(+). In this study, we investigated the conformational heterogeneity of a G-rich sequence from the 5′ unt...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572678/ https://www.ncbi.nlm.nih.gov/pubmed/31126138 http://dx.doi.org/10.3390/molecules24101988 |