Urinary 8-hydroxydeoxyguanosine in relation to XRCC1 rs25487 G/A (Arg399Gln) and OGG1 rs1052133 C/G (Ser326Cys) DNA repair genes polymorphisms in patients with chronic hepatitis C and related hepatocellular carcinoma

Background and aim: DNA repair represents a protective mechanism against cell injury and cancer. 8-hydroxy-deoxyguanosine (8-OHdG) is the main ROS-induced DNA mutation. The current study aimed to evaluate urinary 8-OHdG levels in patients with chronic hepatitis C virus (HCV) and its related hepatoce...

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Detalles Bibliográficos
Autores principales: Mahmoud, Aida A, Hassan, Mohammed H, Ghweil, Ali A, Abdelrahman, Amany, Mohammad, Asmaa N, Ameen, Hesham H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572741/
https://www.ncbi.nlm.nih.gov/pubmed/31354343
http://dx.doi.org/10.2147/CMAR.S209112

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