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Noma in a boy with septic shock: a case report

BACKGROUND: Noma is a rare disease, which is characterized by rapid progression and a high rate of mortality; however, relatively few cases of noma infection accompanied by septic shock in children have been described. Further, most health care professionals have no knowledge of this disease or of i...

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Autores principales: Xu, Lili, Wei, Wanrui, Ge, Xiaohua, Wan, Sibei, Yu, Jing, Zhu, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572743/
https://www.ncbi.nlm.nih.gov/pubmed/31208399
http://dx.doi.org/10.1186/s12887-019-1574-8
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author Xu, Lili
Wei, Wanrui
Ge, Xiaohua
Wan, Sibei
Yu, Jing
Zhu, Xiaodong
author_facet Xu, Lili
Wei, Wanrui
Ge, Xiaohua
Wan, Sibei
Yu, Jing
Zhu, Xiaodong
author_sort Xu, Lili
collection PubMed
description BACKGROUND: Noma is a rare disease, which is characterized by rapid progression and a high rate of mortality; however, relatively few cases of noma infection accompanied by septic shock in children have been described. Further, most health care professionals have no knowledge of this disease or of its clinical significance. CASE PRESENTATION: Herein, we present a case report of a six-year-old male patient who was diagnosed with noma infection at a Chinese pediatric medical intensive care unit (PMICU), at which time, it was discovered that he had septic shock. Following treatment by continuous renal replacement therapy (CRRT) for septic shock arising from noma, the patient was in generally good condition, and the local wound was seen to be essentially healed five weeks post-admission. CONCLUSION: Noma is an opportunistic infectious disease condition. Treatment of the acute phase of noma predominantly focuses on controlling the infection and improving systemic conditions. In addition, CRRT could be considered as a treatment option for cases that present with noma accompanied by septic shock.
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spelling pubmed-65727432019-06-24 Noma in a boy with septic shock: a case report Xu, Lili Wei, Wanrui Ge, Xiaohua Wan, Sibei Yu, Jing Zhu, Xiaodong BMC Pediatr Case Report BACKGROUND: Noma is a rare disease, which is characterized by rapid progression and a high rate of mortality; however, relatively few cases of noma infection accompanied by septic shock in children have been described. Further, most health care professionals have no knowledge of this disease or of its clinical significance. CASE PRESENTATION: Herein, we present a case report of a six-year-old male patient who was diagnosed with noma infection at a Chinese pediatric medical intensive care unit (PMICU), at which time, it was discovered that he had septic shock. Following treatment by continuous renal replacement therapy (CRRT) for septic shock arising from noma, the patient was in generally good condition, and the local wound was seen to be essentially healed five weeks post-admission. CONCLUSION: Noma is an opportunistic infectious disease condition. Treatment of the acute phase of noma predominantly focuses on controlling the infection and improving systemic conditions. In addition, CRRT could be considered as a treatment option for cases that present with noma accompanied by septic shock. BioMed Central 2019-06-17 /pmc/articles/PMC6572743/ /pubmed/31208399 http://dx.doi.org/10.1186/s12887-019-1574-8 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Xu, Lili
Wei, Wanrui
Ge, Xiaohua
Wan, Sibei
Yu, Jing
Zhu, Xiaodong
Noma in a boy with septic shock: a case report
title Noma in a boy with septic shock: a case report
title_full Noma in a boy with septic shock: a case report
title_fullStr Noma in a boy with septic shock: a case report
title_full_unstemmed Noma in a boy with septic shock: a case report
title_short Noma in a boy with septic shock: a case report
title_sort noma in a boy with septic shock: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572743/
https://www.ncbi.nlm.nih.gov/pubmed/31208399
http://dx.doi.org/10.1186/s12887-019-1574-8
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