C/EBPβ-LIP induces cancer-type metabolic reprogramming by regulating the let-7/LIN28B circuit in mice

The transcription factors LAP1, LAP2 and LIP are derived from the Cebpb-mRNA through the use of alternative start codons. High LIP expression has been associated with human cancer and increased cancer incidence in mice. However, how LIP contributes to cellular transformation is poorly understood. He...

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Detalles Bibliográficos
Autores principales: Ackermann, Tobias, Hartleben, Götz, Müller, Christine, Mastrobuoni, Guido, Groth, Marco, Sterken, Britt A., Zaini, Mohamad A., Youssef, Sameh A., Zuidhof, Hidde R., Krauss, Sara R., Kortman, Gertrud, de Haan, Gerald, de Bruin, Alain, Wang, Zhao-Qi, Platzer, Matthias, Kempa, Stefan, Calkhoven, Cornelis F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572810/
https://www.ncbi.nlm.nih.gov/pubmed/31240246
http://dx.doi.org/10.1038/s42003-019-0461-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572810/
https://www.ncbi.nlm.nih.gov/pubmed/31240246
http://dx.doi.org/10.1038/s42003-019-0461-z

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