Targeting the cell cycle in head and neck cancer by Chk1 inhibition: a novel concept of bimodal cell death

Head and neck squamous cell carcinomas (HNSCCs) coincide with poor survival rates. The lack of driver oncogenes complicates the development of targeted treatments for HNSCC. Here, we follow-up on two previous genome-wide RNA and microRNA interference screens in HNSCC to cross-examine tumor-specific...

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Detalles Bibliográficos
Autores principales: van Harten, Anne M., Buijze, Marijke, van der Mast, Richard, Rooimans, Martin A., Martens-de Kemp, Sanne R., Bachas, Costa, Brink, Arjen, Stigter-van Walsum, Marijke, Wolthuis, Rob M. F., Brakenhoff, Ruud H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572811/
https://www.ncbi.nlm.nih.gov/pubmed/31209198
http://dx.doi.org/10.1038/s41389-019-0147-x

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