Programmable mutually exclusive alternative splicing for generating RNA and protein diversity

Alternative splicing performs a central role in expanding genomic coding capacity and proteomic diversity. However, programming of splicing patterns in engineered biological systems remains underused. Synthetic approaches thus far have predominantly focused on controlling expression of a single prot...

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Detalles Bibliográficos
Autores principales: Mathur, Melina, Kim, Cameron M., Munro, Sarah A., Rudina, Shireen S., Sawyer, Eric M., Smolke, Christina D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572816/
https://www.ncbi.nlm.nih.gov/pubmed/31209208
http://dx.doi.org/10.1038/s41467-019-10403-w

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