Exosomes from CD99-deprived Ewing sarcoma cells reverse tumor malignancy by inhibiting cell migration and promoting neural differentiation

Ewing sarcoma (EWS) is an aggressive mesenchymal tumor with unmet clinical need and significant social impacts on children, adolescents, and young adults. CD99, a hallmark surface molecule of EWS, participates in crucial biological processes including cell migration, differentiation, and death. EWS...

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Detalles Bibliográficos
Autores principales: De Feo, Alessandra, Sciandra, Marika, Ferracin, Manuela, Felicetti, Federica, Astolfi, Annalisa, Pignochino, Ymera, Picci, Piero, Carè, Alessandra, Scotlandi, Katia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572819/
https://www.ncbi.nlm.nih.gov/pubmed/31209202
http://dx.doi.org/10.1038/s41419-019-1675-1

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