Cargando…
Contribution of DNA methylation to the expression of FCGRT in human liver and myocardium
FcRn mediates recycling and transcytosis of IgG and albumin in various cell types. The MHC-class-I-like protein of the FcRn heterodimer is encoded by FCGRT. Few determinants of variable FCGRT expression in humans have been identified so far. In this study, we investigated the presence of DNA methyla...
Autores principales: | Cejas, R. B., Ferguson, D. C., Quiñones-Lombraña, A., Bard, J. E., Blanco, J. G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572836/ https://www.ncbi.nlm.nih.gov/pubmed/31209240 http://dx.doi.org/10.1038/s41598-019-45203-1 |
Ejemplares similares
-
Analysis of Response Elements Involved in the Regulation of the Human Neonatal Fc Receptor Gene (FCGRT)
por: Mikulska, Joanna E.
Publicado: (2015) -
Functional humanization of immunoglobulin heavy constant gamma 1 Fc domain human FCGRT transgenic mice
por: Low, Benjamin E., et al.
Publicado: (2020) -
Correction: Analysis of Response Elements Involved in the Regulation of the Human Neonatal Fc Receptor Gene (FCGRT)
por: Mikulska, Joanna E.
Publicado: (2015) -
VNTR2/VNTR3 genotype in the FCGRT gene is associated with reduced effectiveness of intravenous immunoglobulin in patients with myasthenia gravis
por: Su, Shengyao, et al.
Publicado: (2021) -
The importance of FcRn in neuro-immunotherapies: From IgG catabolism, FCGRT gene polymorphisms, IVIg dosing and efficiency to specific FcRn inhibitors
por: Dalakas, Marinos C., et al.
Publicado: (2021)