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Multitask learning and benchmarking with clinical time series data

Health care is one of the most exciting frontiers in data mining and machine learning. Successful adoption of electronic health records (EHRs) created an explosion in digital clinical data available for analysis, but progress in machine learning for healthcare research has been difficult to measure...

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Detalles Bibliográficos
Autores principales: Harutyunyan, Hrayr, Khachatrian, Hrant, Kale, David C., Ver Steeg, Greg, Galstyan, Aram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572845/
https://www.ncbi.nlm.nih.gov/pubmed/31209213
http://dx.doi.org/10.1038/s41597-019-0103-9
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author Harutyunyan, Hrayr
Khachatrian, Hrant
Kale, David C.
Ver Steeg, Greg
Galstyan, Aram
author_facet Harutyunyan, Hrayr
Khachatrian, Hrant
Kale, David C.
Ver Steeg, Greg
Galstyan, Aram
author_sort Harutyunyan, Hrayr
collection PubMed
description Health care is one of the most exciting frontiers in data mining and machine learning. Successful adoption of electronic health records (EHRs) created an explosion in digital clinical data available for analysis, but progress in machine learning for healthcare research has been difficult to measure because of the absence of publicly available benchmark data sets. To address this problem, we propose four clinical prediction benchmarks using data derived from the publicly available Medical Information Mart for Intensive Care (MIMIC-III) database. These tasks cover a range of clinical problems including modeling risk of mortality, forecasting length of stay, detecting physiologic decline, and phenotype classification. We propose strong linear and neural baselines for all four tasks and evaluate the effect of deep supervision, multitask training and data-specific architectural modifications on the performance of neural models.
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spelling pubmed-65728452019-06-21 Multitask learning and benchmarking with clinical time series data Harutyunyan, Hrayr Khachatrian, Hrant Kale, David C. Ver Steeg, Greg Galstyan, Aram Sci Data Analysis Health care is one of the most exciting frontiers in data mining and machine learning. Successful adoption of electronic health records (EHRs) created an explosion in digital clinical data available for analysis, but progress in machine learning for healthcare research has been difficult to measure because of the absence of publicly available benchmark data sets. To address this problem, we propose four clinical prediction benchmarks using data derived from the publicly available Medical Information Mart for Intensive Care (MIMIC-III) database. These tasks cover a range of clinical problems including modeling risk of mortality, forecasting length of stay, detecting physiologic decline, and phenotype classification. We propose strong linear and neural baselines for all four tasks and evaluate the effect of deep supervision, multitask training and data-specific architectural modifications on the performance of neural models. Nature Publishing Group UK 2019-06-17 /pmc/articles/PMC6572845/ /pubmed/31209213 http://dx.doi.org/10.1038/s41597-019-0103-9 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Analysis
Harutyunyan, Hrayr
Khachatrian, Hrant
Kale, David C.
Ver Steeg, Greg
Galstyan, Aram
Multitask learning and benchmarking with clinical time series data
title Multitask learning and benchmarking with clinical time series data
title_full Multitask learning and benchmarking with clinical time series data
title_fullStr Multitask learning and benchmarking with clinical time series data
title_full_unstemmed Multitask learning and benchmarking with clinical time series data
title_short Multitask learning and benchmarking with clinical time series data
title_sort multitask learning and benchmarking with clinical time series data
topic Analysis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572845/
https://www.ncbi.nlm.nih.gov/pubmed/31209213
http://dx.doi.org/10.1038/s41597-019-0103-9
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