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Multitask learning and benchmarking with clinical time series data
Health care is one of the most exciting frontiers in data mining and machine learning. Successful adoption of electronic health records (EHRs) created an explosion in digital clinical data available for analysis, but progress in machine learning for healthcare research has been difficult to measure...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572845/ https://www.ncbi.nlm.nih.gov/pubmed/31209213 http://dx.doi.org/10.1038/s41597-019-0103-9 |
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author | Harutyunyan, Hrayr Khachatrian, Hrant Kale, David C. Ver Steeg, Greg Galstyan, Aram |
author_facet | Harutyunyan, Hrayr Khachatrian, Hrant Kale, David C. Ver Steeg, Greg Galstyan, Aram |
author_sort | Harutyunyan, Hrayr |
collection | PubMed |
description | Health care is one of the most exciting frontiers in data mining and machine learning. Successful adoption of electronic health records (EHRs) created an explosion in digital clinical data available for analysis, but progress in machine learning for healthcare research has been difficult to measure because of the absence of publicly available benchmark data sets. To address this problem, we propose four clinical prediction benchmarks using data derived from the publicly available Medical Information Mart for Intensive Care (MIMIC-III) database. These tasks cover a range of clinical problems including modeling risk of mortality, forecasting length of stay, detecting physiologic decline, and phenotype classification. We propose strong linear and neural baselines for all four tasks and evaluate the effect of deep supervision, multitask training and data-specific architectural modifications on the performance of neural models. |
format | Online Article Text |
id | pubmed-6572845 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-65728452019-06-21 Multitask learning and benchmarking with clinical time series data Harutyunyan, Hrayr Khachatrian, Hrant Kale, David C. Ver Steeg, Greg Galstyan, Aram Sci Data Analysis Health care is one of the most exciting frontiers in data mining and machine learning. Successful adoption of electronic health records (EHRs) created an explosion in digital clinical data available for analysis, but progress in machine learning for healthcare research has been difficult to measure because of the absence of publicly available benchmark data sets. To address this problem, we propose four clinical prediction benchmarks using data derived from the publicly available Medical Information Mart for Intensive Care (MIMIC-III) database. These tasks cover a range of clinical problems including modeling risk of mortality, forecasting length of stay, detecting physiologic decline, and phenotype classification. We propose strong linear and neural baselines for all four tasks and evaluate the effect of deep supervision, multitask training and data-specific architectural modifications on the performance of neural models. Nature Publishing Group UK 2019-06-17 /pmc/articles/PMC6572845/ /pubmed/31209213 http://dx.doi.org/10.1038/s41597-019-0103-9 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Analysis Harutyunyan, Hrayr Khachatrian, Hrant Kale, David C. Ver Steeg, Greg Galstyan, Aram Multitask learning and benchmarking with clinical time series data |
title | Multitask learning and benchmarking with clinical time series data |
title_full | Multitask learning and benchmarking with clinical time series data |
title_fullStr | Multitask learning and benchmarking with clinical time series data |
title_full_unstemmed | Multitask learning and benchmarking with clinical time series data |
title_short | Multitask learning and benchmarking with clinical time series data |
title_sort | multitask learning and benchmarking with clinical time series data |
topic | Analysis |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572845/ https://www.ncbi.nlm.nih.gov/pubmed/31209213 http://dx.doi.org/10.1038/s41597-019-0103-9 |
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