Cargando…

A mass-customizable dermal patch with discrete colorimetric indicators for personalized sweat rate quantification

In this paper, we present a disposable, colorimetric, user-friendly and mass-customizable dermal patch for chronological collection and discrete real-time in situ measurement of sweat secretion over a small area of skin. The patch consists of a laminated filter paper patterned into radially arranged...

Descripción completa

Detalles Bibliográficos
Autores principales: Jain, Vaibhav, Ochoa, Manuel, Jiang, Hongjie, Rahimi, Rahim, Ziaie, Babak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572848/
https://www.ncbi.nlm.nih.gov/pubmed/31240108
http://dx.doi.org/10.1038/s41378-019-0067-0
_version_ 1783427731705298944
author Jain, Vaibhav
Ochoa, Manuel
Jiang, Hongjie
Rahimi, Rahim
Ziaie, Babak
author_facet Jain, Vaibhav
Ochoa, Manuel
Jiang, Hongjie
Rahimi, Rahim
Ziaie, Babak
author_sort Jain, Vaibhav
collection PubMed
description In this paper, we present a disposable, colorimetric, user-friendly and mass-customizable dermal patch for chronological collection and discrete real-time in situ measurement of sweat secretion over a small area of skin. The patch consists of a laminated filter paper patterned into radially arranged channels/fingers with water-activated dyes at their tips. As channels are filled during perspiration, their tips change color once fully saturated, providing easily identifiable levels of water loss which in turn can be mapped to personal dehydration levels. The patch can be manufactured at low cost in a variety of sizes to allow hydration monitoring for individuals participating in activities under different conditions (intensity, temperature, humidity, etc.). Furthermore, we describe an analytical model that enables mass customization of such a flexible wearable system accommodating a broad range of sweat rates and volumes to generate patch designs that are personalized to an individual’s sweat rate, desired time of usage, and the temporal resolution of the required feedback. As a proof-of-concept demonstration, we characterized laser-fabricated patches that cover (7 cm × 5 cm) area of skin having various wicking materials, thicknesses (180–540 µm), and pore sizes (3–11 µm). Tests were conducted at various flow rates simulating different sweating intensities in the range of 1.5–15 mg/cm(2)/min. Experimental results for the case of a half-marathon runner targeting 90 min of usage and sweating at a rate of 1.5 mg/cm(2)/min indicated measurement accuracy of 98.3% when the patch is completely filled.
format Online
Article
Text
id pubmed-6572848
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-65728482019-06-25 A mass-customizable dermal patch with discrete colorimetric indicators for personalized sweat rate quantification Jain, Vaibhav Ochoa, Manuel Jiang, Hongjie Rahimi, Rahim Ziaie, Babak Microsyst Nanoeng Article In this paper, we present a disposable, colorimetric, user-friendly and mass-customizable dermal patch for chronological collection and discrete real-time in situ measurement of sweat secretion over a small area of skin. The patch consists of a laminated filter paper patterned into radially arranged channels/fingers with water-activated dyes at their tips. As channels are filled during perspiration, their tips change color once fully saturated, providing easily identifiable levels of water loss which in turn can be mapped to personal dehydration levels. The patch can be manufactured at low cost in a variety of sizes to allow hydration monitoring for individuals participating in activities under different conditions (intensity, temperature, humidity, etc.). Furthermore, we describe an analytical model that enables mass customization of such a flexible wearable system accommodating a broad range of sweat rates and volumes to generate patch designs that are personalized to an individual’s sweat rate, desired time of usage, and the temporal resolution of the required feedback. As a proof-of-concept demonstration, we characterized laser-fabricated patches that cover (7 cm × 5 cm) area of skin having various wicking materials, thicknesses (180–540 µm), and pore sizes (3–11 µm). Tests were conducted at various flow rates simulating different sweating intensities in the range of 1.5–15 mg/cm(2)/min. Experimental results for the case of a half-marathon runner targeting 90 min of usage and sweating at a rate of 1.5 mg/cm(2)/min indicated measurement accuracy of 98.3% when the patch is completely filled. Nature Publishing Group UK 2019-06-17 /pmc/articles/PMC6572848/ /pubmed/31240108 http://dx.doi.org/10.1038/s41378-019-0067-0 Text en © The Author(s) 2019 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Jain, Vaibhav
Ochoa, Manuel
Jiang, Hongjie
Rahimi, Rahim
Ziaie, Babak
A mass-customizable dermal patch with discrete colorimetric indicators for personalized sweat rate quantification
title A mass-customizable dermal patch with discrete colorimetric indicators for personalized sweat rate quantification
title_full A mass-customizable dermal patch with discrete colorimetric indicators for personalized sweat rate quantification
title_fullStr A mass-customizable dermal patch with discrete colorimetric indicators for personalized sweat rate quantification
title_full_unstemmed A mass-customizable dermal patch with discrete colorimetric indicators for personalized sweat rate quantification
title_short A mass-customizable dermal patch with discrete colorimetric indicators for personalized sweat rate quantification
title_sort mass-customizable dermal patch with discrete colorimetric indicators for personalized sweat rate quantification
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572848/
https://www.ncbi.nlm.nih.gov/pubmed/31240108
http://dx.doi.org/10.1038/s41378-019-0067-0
work_keys_str_mv AT jainvaibhav amasscustomizabledermalpatchwithdiscretecolorimetricindicatorsforpersonalizedsweatratequantification
AT ochoamanuel amasscustomizabledermalpatchwithdiscretecolorimetricindicatorsforpersonalizedsweatratequantification
AT jianghongjie amasscustomizabledermalpatchwithdiscretecolorimetricindicatorsforpersonalizedsweatratequantification
AT rahimirahim amasscustomizabledermalpatchwithdiscretecolorimetricindicatorsforpersonalizedsweatratequantification
AT ziaiebabak amasscustomizabledermalpatchwithdiscretecolorimetricindicatorsforpersonalizedsweatratequantification
AT jainvaibhav masscustomizabledermalpatchwithdiscretecolorimetricindicatorsforpersonalizedsweatratequantification
AT ochoamanuel masscustomizabledermalpatchwithdiscretecolorimetricindicatorsforpersonalizedsweatratequantification
AT jianghongjie masscustomizabledermalpatchwithdiscretecolorimetricindicatorsforpersonalizedsweatratequantification
AT rahimirahim masscustomizabledermalpatchwithdiscretecolorimetricindicatorsforpersonalizedsweatratequantification
AT ziaiebabak masscustomizabledermalpatchwithdiscretecolorimetricindicatorsforpersonalizedsweatratequantification