Cargando…
A mass-customizable dermal patch with discrete colorimetric indicators for personalized sweat rate quantification
In this paper, we present a disposable, colorimetric, user-friendly and mass-customizable dermal patch for chronological collection and discrete real-time in situ measurement of sweat secretion over a small area of skin. The patch consists of a laminated filter paper patterned into radially arranged...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572848/ https://www.ncbi.nlm.nih.gov/pubmed/31240108 http://dx.doi.org/10.1038/s41378-019-0067-0 |
_version_ | 1783427731705298944 |
---|---|
author | Jain, Vaibhav Ochoa, Manuel Jiang, Hongjie Rahimi, Rahim Ziaie, Babak |
author_facet | Jain, Vaibhav Ochoa, Manuel Jiang, Hongjie Rahimi, Rahim Ziaie, Babak |
author_sort | Jain, Vaibhav |
collection | PubMed |
description | In this paper, we present a disposable, colorimetric, user-friendly and mass-customizable dermal patch for chronological collection and discrete real-time in situ measurement of sweat secretion over a small area of skin. The patch consists of a laminated filter paper patterned into radially arranged channels/fingers with water-activated dyes at their tips. As channels are filled during perspiration, their tips change color once fully saturated, providing easily identifiable levels of water loss which in turn can be mapped to personal dehydration levels. The patch can be manufactured at low cost in a variety of sizes to allow hydration monitoring for individuals participating in activities under different conditions (intensity, temperature, humidity, etc.). Furthermore, we describe an analytical model that enables mass customization of such a flexible wearable system accommodating a broad range of sweat rates and volumes to generate patch designs that are personalized to an individual’s sweat rate, desired time of usage, and the temporal resolution of the required feedback. As a proof-of-concept demonstration, we characterized laser-fabricated patches that cover (7 cm × 5 cm) area of skin having various wicking materials, thicknesses (180–540 µm), and pore sizes (3–11 µm). Tests were conducted at various flow rates simulating different sweating intensities in the range of 1.5–15 mg/cm(2)/min. Experimental results for the case of a half-marathon runner targeting 90 min of usage and sweating at a rate of 1.5 mg/cm(2)/min indicated measurement accuracy of 98.3% when the patch is completely filled. |
format | Online Article Text |
id | pubmed-6572848 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-65728482019-06-25 A mass-customizable dermal patch with discrete colorimetric indicators for personalized sweat rate quantification Jain, Vaibhav Ochoa, Manuel Jiang, Hongjie Rahimi, Rahim Ziaie, Babak Microsyst Nanoeng Article In this paper, we present a disposable, colorimetric, user-friendly and mass-customizable dermal patch for chronological collection and discrete real-time in situ measurement of sweat secretion over a small area of skin. The patch consists of a laminated filter paper patterned into radially arranged channels/fingers with water-activated dyes at their tips. As channels are filled during perspiration, their tips change color once fully saturated, providing easily identifiable levels of water loss which in turn can be mapped to personal dehydration levels. The patch can be manufactured at low cost in a variety of sizes to allow hydration monitoring for individuals participating in activities under different conditions (intensity, temperature, humidity, etc.). Furthermore, we describe an analytical model that enables mass customization of such a flexible wearable system accommodating a broad range of sweat rates and volumes to generate patch designs that are personalized to an individual’s sweat rate, desired time of usage, and the temporal resolution of the required feedback. As a proof-of-concept demonstration, we characterized laser-fabricated patches that cover (7 cm × 5 cm) area of skin having various wicking materials, thicknesses (180–540 µm), and pore sizes (3–11 µm). Tests were conducted at various flow rates simulating different sweating intensities in the range of 1.5–15 mg/cm(2)/min. Experimental results for the case of a half-marathon runner targeting 90 min of usage and sweating at a rate of 1.5 mg/cm(2)/min indicated measurement accuracy of 98.3% when the patch is completely filled. Nature Publishing Group UK 2019-06-17 /pmc/articles/PMC6572848/ /pubmed/31240108 http://dx.doi.org/10.1038/s41378-019-0067-0 Text en © The Author(s) 2019 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Jain, Vaibhav Ochoa, Manuel Jiang, Hongjie Rahimi, Rahim Ziaie, Babak A mass-customizable dermal patch with discrete colorimetric indicators for personalized sweat rate quantification |
title | A mass-customizable dermal patch with discrete colorimetric indicators for personalized sweat rate quantification |
title_full | A mass-customizable dermal patch with discrete colorimetric indicators for personalized sweat rate quantification |
title_fullStr | A mass-customizable dermal patch with discrete colorimetric indicators for personalized sweat rate quantification |
title_full_unstemmed | A mass-customizable dermal patch with discrete colorimetric indicators for personalized sweat rate quantification |
title_short | A mass-customizable dermal patch with discrete colorimetric indicators for personalized sweat rate quantification |
title_sort | mass-customizable dermal patch with discrete colorimetric indicators for personalized sweat rate quantification |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572848/ https://www.ncbi.nlm.nih.gov/pubmed/31240108 http://dx.doi.org/10.1038/s41378-019-0067-0 |
work_keys_str_mv | AT jainvaibhav amasscustomizabledermalpatchwithdiscretecolorimetricindicatorsforpersonalizedsweatratequantification AT ochoamanuel amasscustomizabledermalpatchwithdiscretecolorimetricindicatorsforpersonalizedsweatratequantification AT jianghongjie amasscustomizabledermalpatchwithdiscretecolorimetricindicatorsforpersonalizedsweatratequantification AT rahimirahim amasscustomizabledermalpatchwithdiscretecolorimetricindicatorsforpersonalizedsweatratequantification AT ziaiebabak amasscustomizabledermalpatchwithdiscretecolorimetricindicatorsforpersonalizedsweatratequantification AT jainvaibhav masscustomizabledermalpatchwithdiscretecolorimetricindicatorsforpersonalizedsweatratequantification AT ochoamanuel masscustomizabledermalpatchwithdiscretecolorimetricindicatorsforpersonalizedsweatratequantification AT jianghongjie masscustomizabledermalpatchwithdiscretecolorimetricindicatorsforpersonalizedsweatratequantification AT rahimirahim masscustomizabledermalpatchwithdiscretecolorimetricindicatorsforpersonalizedsweatratequantification AT ziaiebabak masscustomizabledermalpatchwithdiscretecolorimetricindicatorsforpersonalizedsweatratequantification |