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Functional roles of hnRNPA2/B1 regulated by METTL3 in mammalian embryonic development

Heterogeneous nuclear ribonucleoprotein A2/B1 (hnRNPA2/B1) plays an important role in RNA processing via in m(6)A modification of pre-mRNA or pre-miRNA. However, the functional role of and relationship between m(6)A and hnRNPA2/B1 in early embryonic development are unclear. Here, we found that hnRNP...

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Detalles Bibliográficos
Autores principales: Kwon, Jeongwoo, Jo, Yu-Jin, Namgoong, Suk, Kim, Nam-Hyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572863/
https://www.ncbi.nlm.nih.gov/pubmed/31201338
http://dx.doi.org/10.1038/s41598-019-44714-1