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Etiology and outcomes of convulsive status epilepticus in children
OBJECTIVE: The study aimed to ascertain different causes and outcomes of convulsive status epilepticus in children. METHODS: From January 2018 to June 2018, seventy three patients who presented with status epilepticus were studied. Data were recorded with the help of a pre-formed performa. Etiologic...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Professional Medical Publications
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572953/ https://www.ncbi.nlm.nih.gov/pubmed/31258564 http://dx.doi.org/10.12669/pjms.35.3.120 |
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author | Uzair, Muhammad Ibrahim, Asif Zafar, Faisal Sultan, Tipu |
author_facet | Uzair, Muhammad Ibrahim, Asif Zafar, Faisal Sultan, Tipu |
author_sort | Uzair, Muhammad |
collection | PubMed |
description | OBJECTIVE: The study aimed to ascertain different causes and outcomes of convulsive status epilepticus in children. METHODS: From January 2018 to June 2018, seventy three patients who presented with status epilepticus were studied. Data were recorded with the help of a pre-formed performa. Etiological factors and outcomes in terms of recovery, morbidity and mortality were studied. RESULTS: Out of 73 children, forty one (56%) were males and 32(44%) were females with median age of 1.09±0.27 years. Etiologies were acute symptomatic 25(34%), febrile 19(26%), progressive encephalopathy 10(14%), remote symptomatic 10(14%) and idiopathic 7 (9%) with p-value 0.005. Status epilepticus was controlled within one hour in 42(57%), within 1-6 hours in 21(29%) and more than 6 hours in 10(14%) patients with p-value 0.027. During hospitals stay, twenty one (29%) patients recovered completely, seizure recurred in 12(16%), Twelve (16%) became mentally retarded, Twelve (16%) developed mental retardation along with seizures and 16(22%) died. Eight (10.9%) deaths were attributed to acute symptomatic etiology with p-value less than 0.001. CONCLUSION: This study concluded that acute symptomatic etiology was more common cause of status epilepticus as compared to other etiologies and it is associated with poorer outcomes as compared to other etiologies. |
format | Online Article Text |
id | pubmed-6572953 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Professional Medical Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-65729532019-06-28 Etiology and outcomes of convulsive status epilepticus in children Uzair, Muhammad Ibrahim, Asif Zafar, Faisal Sultan, Tipu Pak J Med Sci Original Article OBJECTIVE: The study aimed to ascertain different causes and outcomes of convulsive status epilepticus in children. METHODS: From January 2018 to June 2018, seventy three patients who presented with status epilepticus were studied. Data were recorded with the help of a pre-formed performa. Etiological factors and outcomes in terms of recovery, morbidity and mortality were studied. RESULTS: Out of 73 children, forty one (56%) were males and 32(44%) were females with median age of 1.09±0.27 years. Etiologies were acute symptomatic 25(34%), febrile 19(26%), progressive encephalopathy 10(14%), remote symptomatic 10(14%) and idiopathic 7 (9%) with p-value 0.005. Status epilepticus was controlled within one hour in 42(57%), within 1-6 hours in 21(29%) and more than 6 hours in 10(14%) patients with p-value 0.027. During hospitals stay, twenty one (29%) patients recovered completely, seizure recurred in 12(16%), Twelve (16%) became mentally retarded, Twelve (16%) developed mental retardation along with seizures and 16(22%) died. Eight (10.9%) deaths were attributed to acute symptomatic etiology with p-value less than 0.001. CONCLUSION: This study concluded that acute symptomatic etiology was more common cause of status epilepticus as compared to other etiologies and it is associated with poorer outcomes as compared to other etiologies. Professional Medical Publications 2019 /pmc/articles/PMC6572953/ /pubmed/31258564 http://dx.doi.org/10.12669/pjms.35.3.120 Text en Copyright: © Pakistan Journal of Medical Sciences http://creativecommons.org/licenses/by/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Uzair, Muhammad Ibrahim, Asif Zafar, Faisal Sultan, Tipu Etiology and outcomes of convulsive status epilepticus in children |
title | Etiology and outcomes of convulsive status epilepticus in children |
title_full | Etiology and outcomes of convulsive status epilepticus in children |
title_fullStr | Etiology and outcomes of convulsive status epilepticus in children |
title_full_unstemmed | Etiology and outcomes of convulsive status epilepticus in children |
title_short | Etiology and outcomes of convulsive status epilepticus in children |
title_sort | etiology and outcomes of convulsive status epilepticus in children |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572953/ https://www.ncbi.nlm.nih.gov/pubmed/31258564 http://dx.doi.org/10.12669/pjms.35.3.120 |
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