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DEAD-box RNA helicase Belle posttranscriptionally promotes gene expression in an ATPase activity-dependent manner

Drosophila Belle (human ortholog DDX3) is a conserved DEAD-box RNA helicase implicated in regulating gene expression. However, the molecular mechanisms by which Belle/DDX3 regulates gene expression are poorly understood. Here we performed systematic mutational analysis to determine the contributions...

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Detalles Bibliográficos
Autores principales: Liao, Susan E., Kandasamy, Suresh K., Zhu, Li, Fukunaga, Ryuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6573787/
https://www.ncbi.nlm.nih.gov/pubmed/30979781
http://dx.doi.org/10.1261/rna.070268.118