Cargando…
Age-related late-onset disease heritability patterns and implications for genome-wide association studies
Genome-wide association studies (GWASs) and other computational biology techniques are gradually discovering the causal gene variants that contribute to late-onset human diseases. After more than a decade of genome-wide association study efforts, these can account for only a fraction of the heritabi...
Autor principal: | Oliynyk, Roman Teo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6573810/ https://www.ncbi.nlm.nih.gov/pubmed/31231601 http://dx.doi.org/10.7717/peerj.7168 |
Ejemplares similares
-
Evaluating the Potential of Younger Cases and Older Controls Cohorts to Improve Discovery Power in Genome-Wide Association Studies of Late-Onset Diseases
por: Oliynyk, Roman Teo
Publicado: (2019) -
Quantifying the Potential for Future Gene Therapy to Lower Lifetime Risk of Polygenic Late-Onset Diseases
por: Oliynyk, Roman Teo
Publicado: (2019) -
Genome-wide analysis of the hypoxia-related DNA methylation-driven genes in lung adenocarcinoma progression
por: Li, Hongxia, et al.
Publicado: (2020) -
Weighted multiple testing procedures in genome-wide association studies
por: Obry, Ludivine, et al.
Publicado: (2023) -
The regulatory genome constrains protein sequence evolution: implications for the search for disease-associated genes
por: Evans, Patrick, et al.
Publicado: (2020)