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Lubiprostone as a potential therapeutic agent to improve intestinal permeability and prevent the development of atherosclerosis in apolipoprotein E-deficient mice
The interaction between atherosclerosis and commensal microbes through leaky gut syndrome (LGS), which is characterized by impaired intestinal permeability and the introduction of undesired pathogens into the body, has not been fully elucidated. Our aim was to investigate the potential role of a ClC...
Autores principales: | Arakawa, Kentaro, Ishigami, Tomoaki, Nakai-Sugiyama, Michiko, Chen, Lin, Doi, Hiroshi, Kino, Tabito, Minegishi, Shintaro, Saigoh-Teranaka, Sae, Sasaki-Nakashima, Rie, Hibi, Kiyoshi, Kimura, Kazuo, Tamura, Kouichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6576757/ https://www.ncbi.nlm.nih.gov/pubmed/31206525 http://dx.doi.org/10.1371/journal.pone.0218096 |
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